Rheological investigation of a versatile salecan/curdlan gel matrix

被引:26
|
作者
Fan, Zhiping [1 ]
Cheng, Ping [2 ]
Prakash, Sangeeta [3 ]
Zhang, Pan [1 ]
Mei, Leixia [1 ]
Ji, Shilei [1 ]
Wang, Zhengping [1 ]
Han, Jun [1 ]
机构
[1] Liaocheng Univ, Inst BioPharmaceut Res, Liaocheng 252059, Shandong, Peoples R China
[2] Liaocheng High Tech Biotechnol Co Ltd, Liaocheng 252059, Shandong, Peoples R China
[3] Univ Queensland, Sch Agr & Food Sci, Brisbane, Qld 4072, Australia
关键词
Hydrogel; Rheology; Salecan; Curdlan; Composites; GUM HYDROGELS; POLYSACCHARIDE; DELIVERY; ALGINATE;
D O I
10.1016/j.ijbiomac.2021.11.051
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Hydrogel, as a three-dimensional material with high water content, has unique physicochemical and variable mechanical properties. Natural polysaccharide-based composite hydrogels are very popular within medical industry as these viscoelastic materials are non-toxic, biodegradable, bioabsorbable, and biocompatible. This research investigates the engineering of novel composite hydrogels from natural polysaccharides salecan and curdlan without any structural modification and chemical crosslinking. The scanning electron microscopy, Fourier transform infrared spectroscopy and various rheological methods were employed to investigate the morphology, molecular interaction, and flow behavior of the samples respectively. The key rheological parameters were compared using the Power Law, Herschel-Bulkley and Arrhenius models. This is the first study reporting a novel composite hydrogel made from Salecan and Curdlan with ideal elasticity, enhanced thermostability, good injectability, self-recovery and other rheological properties that will pave the way for application in different fields.
引用
收藏
页码:2202 / 2209
页数:8
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