Bared essentials of CDK2 and cyclin E

被引:33
|
作者
Roberts, JM
Sherr, CJ
机构
[1] Fred Hutchinson Canc Res Ctr, Div Basic Sci, Seattle, WA 98104 USA
[2] Howard Hughes Med Inst, Chevy Chase, MD 20815 USA
[3] St Jude Childrens Res Hosp, Dept Genet & Tumor Cell Biol, Memphis, TN 38105 USA
关键词
D O I
10.1038/ng1234
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The cyclin E-CDK2 complex was thought to be an essential regulator of the mitotic cell cycle. Surprisingly, disabling the critical genes in the mouse has fewer effects than anticipated.
引用
收藏
页码:9 / 10
页数:2
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