HilbertCurve: an R/Bioconductor package for high-resolution visualization of genomic data

被引:21
作者
Gu, Zuguang [1 ,2 ]
Eils, Roland [1 ,2 ,3 ,4 ]
Schlesner, Matthias [1 ,2 ]
机构
[1] German Canc Res Ctr, Div Theoret Bioinformat, Heidelberg, Germany
[2] German Canc Res Ctr, Heidelberg Ctr Personalized Oncol DKFZ HIPO, Heidelberg, Germany
[3] Heidelberg Univ, IPMB, Dept Bioinformat & Funct Genom, Heidelberg, Germany
[4] Heidelberg Univ, BioQuant, Heidelberg, Germany
关键词
D O I
10.1093/bioinformatics/btw161
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Hilbert curves enable high-resolution visualization of genomic data on a chromosomeor genome-wide scale. Here we present the HilbertCurve package that provides an easy-to-use interface for mapping genomic data to Hilbert curves. The package transforms the curve as a virtual axis, thereby hiding the details of the curve construction from the user. HilbertCurve supports multiple-layer overlay that makes it a powerful tool to correlate the spatial distribution of multiple feature types. Availability and implementation: The HilbertCurve package and documentation are freely available from the Bioconductor project: http://www.bioconductor.org/packages/devel/bioc/html/HilbertCurve.html
引用
收藏
页码:2372 / 2374
页数:3
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