Synthesis of Si-substituted hydroxyapatite by a wet mechanochemical method

被引：51

作者：

Tian, Ting ^{[1
]}

Jiang, Dongliang ^{[1
]}

Zhang, Jingxian ^{[1
]}

Lin, Qingling ^{[1
]}

机构：

[1] Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China

来源：

MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS | 2008年 / 28卷 / 01期

关键词：

biomedical applications; apatite; silicate; ion substitutions; inductively coupled plasma;

D O I：

10.1016/j.msec.2007.10.049

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Si-substituted hydroxyapatites with up to 2.0 wt% Si content, have been prepared by a wet mechanochemical method to obtain improved biocompatibility. From XRD, ICP and FTIR analysis, single phase of modified hydroxyapatite with PO43- partially substituted by SiO44- was confirmed. The XRD data indicated that some changes take place in the HA lattice with varying Si contents in Si-HA samples. The in-vitro bioactivity of the as-obtained materials was determined by soaking the materials in SBF, monitoring the changes of chemical composition and pH value of the SBF solution, whereas the microstructures of the soaked powders were observed by TEM. (C) 2007 Published by Elsevier B.V.

引用

页码：57 / 63

页数：7

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