Strategies for the development of a peptide computer

被引:15
作者
Hug, H
Schuler, R
机构
[1] Univ Ulm, Kinderklin, D-89075 Ulm, Germany
[2] Univ Ulm, Abo Theoret Informat, D-89069 Ulm, Germany
关键词
D O I
10.1093/bioinformatics/17.4.364
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Motivation: We devise a computational model using protein-protein interactions. Results: Peptide-antibody interactions can be used to perform a large number of small logical operations in parallel. We show for example how a sequence of operations can be used to compare the number of occurrences of an element in two sets and how to estimate the number of occurrences of an element in a set. Similar to DNA-computing, these techniques could in principle be extended to solve instances of NP-complete problems. We give as an example a procedure to solve examples of the satisfiability problem.
引用
收藏
页码:364 / 368
页数:5
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