Micronization of polyethylene glycol by PGSS (Particles from Gas Saturated Solutions)-drying of aqueous solutions

被引：31

作者：

Martin, Angel ^{[1
]}

Huu Minh Pham ^{[1
]}

Kilzer, Andreas ^{[1
]}

Kareth, Sabine ^{[1
]}

Weidner, Eckhard ^{[1
]}

机构：

[1] Ruhr Univ Bochum, D-44801 Bochum, Germany

来源：

CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION | 2010年 / 49卷 / 12期

关键词：

Supercritical carbon dioxide; Static mixer; Spray tower; Precipitation; Atomization; Mass transfer; SUPERCRITICAL FLUIDS; PHASE-EQUILIBRIUM; CARBON-DIOXIDE; COPRECIPITATION; TEMPERATURE; PARTICLES; PEG; CO2;

D O I：

10.1016/j.cep.2010.09.014

中图分类号：

TE [石油、天然气工业]; TK [能源与动力工程];

学科分类号：

0807 ; 0820 ;

摘要：

Micronization of polyethylene glycol from aqueous solutions has been successfully performed with a Particles from Gas Saturated Solutions (PGSS)-drying process, producing spherical PEG particles with average particle size of 10 mu m and residual water content below 1 wt%. A detailed experimental analysis of the influence of different process and design parameters (temperature, pressure, flow rates, design of the static mixer used to put into contact aqueous solution and CO2) has been carried out. Smaller particles were obtained when carbon dioxide/solution ratio, pressure and temperature were increased. The residual humidity in the product decreased when carbon dioxide/solution ratio and temperature were increased and when pressure was decreased. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：1259 / 1266

页数：8

共 25 条

[1] Lyophilization of polyethylene glycol mixtures [J].