'One-pot' ultrasound irradiation promoted synthesis and spectral characterization of an array of novel 1,1′-(5,5′-(1,4-phenylene)bis(3-aryl-1H-pyrazole-5,1(4H,5H)-diyl))diethanones, a bis acetylated pyrazoles derivatives

An array of novel 1,1'-(5,5'-(1,4-phenylene)bis(3-aryl-1H-pyrazole-5,1(4H,5H)-diyl))diethanones, a bis acetylated pyrazoles derivatives are synthesized in 'one-pot' by ultrasound irradiation method and are characterized by melting point, elemental analysis, MS. FT-IR, one-dimensional NMR (H-1 and C-13) and two-dimensional NOESY spectra. The methylene and methane protons of pyrazoles moiety splits signal as ABX pattern in the proton NMR spectra and the key nOe correlations are confirmed by NOESY spectrum. (C) 2010 Elsevier B.V. All rights reserved.