Sedation During Neurocritical Care

被引：5
作者：
Vanaclocha, Nieves [1 ]
Chisbert, Vicente [2 ]
Quilis, Vicent [3 ,4 ,5 ]
Bilotta, Federico [6 ]
Badenes, Rafael [7 ]
机构：
[1] Hosp Univ Politecn La Fe, Dept Plast Reconstruct Surg, Valencia, Spain
[2] Univ Catolica Valencia, Escuela Doctorado, Valencia, Spain
[3] Hosp Clin Univ Valencia, Dept Neurosurg, Valencia, Spain
[4] Mayo Clin, Coll Med & Sci, Rochester, MN USA
[5] Univ Valencia, Dept Human Anat & Embryol, Fac Med, Valencia, Spain
[6] Univ Roma La Sapienza, Dept Anesthesiol, Rome, Italy
[7] Univ Valencia, Hosp Clin Univ Valencia, Dept Anesthesiol & Surg Trauma Intens Care, Valencia, Spain
来源：
JOURNAL OF NEUROANAESTHESIOLOGY AND CRITICAL CARE | 2019年 / 6卷 / 01期
关键词：
sedative agents; neurocritical care; neurointensive care unit; neurological wakeup test;
D O I：
10.1055/s-0039-1688897
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
Sedation is an essential therapeutic strategy in the care of neurocritical patients. Intravenous sedative agents are the most widely used, with promising alternatives (dexmedetomidine, ketamine, and volatile agents) to propofol and midazolam arising. Studies designed to evaluate superiority and avoid biases are required. A neurological awakening test is safe in most patients. Potential risks and benefits of limiting deep sedation and daily interruption of sedation in these patients remain unclear. The aim of this review was to report recent clinical evidence on sedation in this subgroup of patients, focusing on its effects on clinical prognosis.
引用
收藏
页码：56 / 61
页数：6
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