From transformation to chronification of migraine: pathophysiological and clinical aspects

被引：80
作者：
Torres-Ferrus, M. [1 ]
Ursitti, F. [2 ]
Alpuente-Ruiz, A. [1 ]
Brunello, F. [3 ]
Chiappino, D. [4 ]
de Vries, T. [5 ]
Di Marco, S. [6 ]
Ferlisi, S. [6 ]
Guerritore, L. [4 ]
Gonzalez-Garcia, N. [7 ]
Gonzalez-Martinez, A. [8 ,9 ]
Khutorov, D. [10 ]
Kritsilis, M. [11 ]
Kyrou, A. [12 ]
Makeeva, T. [13 ]
Minguez-Olaondo, A. [14 ,15 ,16 ]
Pilati, L. [6 ]
Serrien, A. [17 ]
Tsurkalenko, O. [18 ]
Van den Abbeele, D. [19 ]
van Hoogstraten, W. S. [20 ]
Lampl, C. [21 ]
机构：
[1] Univ Autonoma Barcelona, Headache & Craniofacial Pain Unit, Vall dHebron Res Inst VHIR,Dept Med, Hosp Univ Vall dHebron,Neurol Dept,Headache & Neu, Barcelona, Spain
[2] Bambino Gesu Pediat Hosp, Headache Ctr, Child Neurol Unit, Rome, Italy
[3] Univ Hosp Padua, Juvenile Headache Ctr, Dept Womans & Childs Hlth, Padua, Italy
[4] Univ Rome Sapienza, St Andrea Hosp, Dept Internal Med, Rome, Italy
[5] Erasmus MC, Dept Internal Med, Div Vasc Med & Pharmacol, Rotterdam, Netherlands
[6] Univ Palermo, Policlin Paolo Giaccone Hosp, Dept Biomed Neurosci & Adv Diagnost, Palermo, Italy
[7] Hosp Univ Clin San Carlos, Neurol Dept, Headache & Craniofacial Pain Unit, Madrid, Spain
[8] Univ Autonoma Madrid UAM, Hosp Univ La Princesa, Neurol Dept, Madrid, Spain
[9] Univ Autonoma Madrid UAM, Inst Invest Sanit La Princesa, Madrid, Spain
[10] Nikiforov Russian Ctr Emergency & Radiat Med EMER, Dept Clin Neurol & Sleep Med, St Petersburg, Russia
[11] Grevena Gen Hosp, Grevena, Greece
[12] Univ Bern, Univ Hosp Psychiat & Psychotherapy, Switzerland Univ Hosp Psychiat, Bern, Switzerland
[13] Med Ctr New Med Technol, Dept Neurol, Headache Unit, Voronezh, Russia
[14] Univ Hosp Donostia, Dept Neurol, San Sebastian, Spain
[15] Clin Univ Navarra, Dept Neurol, Pamplona, Spain
[16] Hosp Quironsalud Donostia, Dept Neurol, San Sebastian, Spain
[17] Univ Hosp Leuven, Dept Neurol, Leuven, Belgium
[18] State Inst Dnipropetrovsk Med Akad MOH Ukraine, Dept Neurol & Neurosurg, Dnipro, Ukraine
[19] Ghent Univ Hosp, Dept Neurol, Ghent, Belgium
[20] Erasmus MC, Dept Neurosci, Rotterdam, Netherlands
[21] Ordensklinikum Linz Barmherzige Schwestern, Headache Med Ctr Linz, Linz, Austria
来源：
JOURNAL OF HEADACHE AND PAIN | 2020年 / 21卷 / 01期
关键词：
Chronic migraine; Transformation; Pathophysiology; Risk factors; Genetics; Biomarker; Neurophysiology; Neuroimaging; Animal models; GENOME-WIDE ASSOCIATION; GENE-RELATED PEPTIDE; BLOOD-BRAIN-BARRIER; CHRONIC DAILY HEADACHE; TUMOR-NECROSIS-FACTOR; EPISODIC MIGRAINE; SUSCEPTIBILITY LOCI; AMERICAN MIGRAINE; PERIPHERAL-BLOOD; INTERNATIONAL BURDEN;
D O I：
10.1186/s10194-020-01111-8
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Chronic migraine is a neurological disorder characterized by 15 or more headache days per month of which at least 8 days show typical migraine features. The process that describes the development from episodic migraine into chronic migraine is commonly referred to as migraine transformation or chronification. Ample studies have attempted to identify factors associated with migraine transformation from different perspectives. Understanding CM as a pathological brain state with trigeminovascular participation where biological changes occur, we have completed a comprehensive review on the clinical, epidemiological, genetic, molecular, structural, functional, physiological and preclinical evidence available.
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页数：12
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共 155 条
  • [1] Conductivity, memristivity and creativity in cellular automata
    Adamatzky, Andrew
    [J]. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 2014, 8751 : 1 - 5
  • [2] Dopamine and migraine: biology and clinical implications
    Akerman, S.
    Goadsby, P. J.
    [J]. CEPHALALGIA, 2007, 27 (11) : 1308 - 1314
  • [3] Intact blood-brain barrier during spontaneous attacks of migraine without aura: a 3T DCE-MRI study
    Amin, F. M.
    Hougaard, A.
    Cramer, S. P.
    Christensen, C. E.
    Wolfram, F.
    Larsson, H. B. W.
    Ashina, M.
    [J]. EUROPEAN JOURNAL OF NEUROLOGY, 2017, 24 (09) : 1116 - 1124
  • [4] Genome-wide meta-analysis identifies new susceptibility loci for migraine
    Anttila, Verneri
    Winsvold, Bendik S.
    Gormley, Padhraig
    Kurth, Tobias
    Bettella, Francesco
    McMahon, George
    Kallela, Mikko
    Malik, Rainer
    de Vries, Boukje
    Terwindt, Gisela
    Medland, Sarah E.
    Todt, Unda
    McArdle, Wendy L.
    Quaye, Lydia
    Koiranen, Markku
    Ikram, M. Arfan
    Lehtimaki, Terho
    Stam, Anine H.
    Ligthart, Lannie
    Wedenoja, Juho
    Dunham, Ian
    Neale, Benjamin M.
    Palta, Priit
    Hamalainen, Eija
    Schuerks, Markus
    Rose, Lynda M.
    Buring, Julie E.
    Ridker, Paul M.
    Steinberg, Stacy
    Stefansson, Hreinn
    Jakobsson, Finnbogi
    Lawlor, Debbie A.
    Evans, David M.
    Ring, Susan M.
    Farkkila, Markus
    Artto, Ville
    Kaunisto, Mari A.
    Freilinger, Tobias
    Schoenen, Jean
    Frants, Rune R.
    Pelzer, Nadine
    Weller, Claudia M.
    Zielman, Ronald
    Heath, Andrew C.
    Madden, Pamela A. F.
    Montgomery, Grant W.
    Martin, Nicholas G.
    Borck, Guntram
    Goebel, Hartmut
    Heinze, Axel
    [J]. NATURE GENETICS, 2013, 45 (08) : 912 - U255
  • [5] Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1
    Anttila, Verneri
    Stefansson, Hreinn
    Kallela, Mikko
    Todt, Unda
    Terwindt, Gisela M.
    Calafato, M. Stella
    Nyholt, Dale R.
    Dimas, Antigone S.
    Freilinger, Tobias
    Mueller-Myhsok, Bertram
    Artto, Ville
    Inouye, Michael
    Alakurtti, Kirsi
    Kaunisto, Mari A.
    Haemaelaeinen, Eija
    de Vries, Boukje
    Stam, Anine H.
    Weller, Claudia M.
    Heinze, Axel
    Heinze-Kuhn, Katja
    Goebel, Ingrid
    Borck, Guntram
    Goebel, Hartmut
    Steinberg, Stacy
    Wolf, Christiane
    Bjoernsson, Asgeir
    Gudmundsson, Gretar
    Kirchmann, Malene
    Hauge, Anne
    Werge, Thomas
    Schoenen, Jean
    Eriksson, Johan G.
    Hagen, Knut
    Stovner, Lars
    Wichmann, Erich
    Meitinger, Thomas
    Alexander, Michael
    Moebus, Susanne
    Schreiber, Stefan
    Aulchenko, Yurii S.
    Breteler, Monique M. B.
    Uitterlinden, Andre G.
    Hofman, Albert
    van Duijn, Cornelia M.
    Tikka-Kleemola, Paevi
    Vepsaelaeinen, Salli
    Lucae, Susanne
    Tozzi, Federica
    Muglia, Pierandrea
    Barrett, Jeffrey
    [J]. NATURE GENETICS, 2010, 42 (10) : 869 - +
  • [6] Brainstem dysfunction in chronic migraine as evidenced by neurophysiological and positron emission tomography studies
    Aurora, Sheena K.
    Barrodale, Patricia M.
    Tipton, Reda L.
    Khodavirdi, Ani
    [J]. HEADACHE, 2007, 47 (07): : 996 - 1003
  • [7] Chronic Migraine: An Update on Physiology, Imaging, and the Mechanism of Action of Two Available Pharmacologic Therapies
    Aurora, Sheena K.
    Brin, Mitchell F.
    [J]. HEADACHE, 2017, 57 (01): : 109 - 125
  • [8] Cortical inhibition is reduced in chronic and episodic migraine and demonstrates a spectrum of illness
    Aurora, SK
    Barrodale, P
    Chronicle, EP
    Mulleners, WM
    [J]. HEADACHE, 2005, 45 (05): : 546 - 552
  • [9] Prevalence and characteristics of allodynia in headache sufferers - A population study
    Bigal, M. E.
    Ashina, S.
    Burstein, R.
    Reed, M. L.
    Buse, D.
    Serrano, D.
    Lipton, R. B.
    [J]. NEUROLOGY, 2008, 70 (17) : 1525 - 1533
  • [10] Clinical course in migraine: Conceptualizing migraine transformation
    Bigal, Marcelo E.
    Lipton, Richard B.
    [J]. NEUROLOGY, 2008, 71 (11) : 848 - 855
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