Room-temperature growth of covalent organic frameworks as the stationary phase for open-tubular capillary electrochromatography

被引:13
作者
Li, Qiaoyan [1 ,2 ,3 ]
Li, Zhentao [1 ,2 ,3 ]
Fu, Yuanyuan [1 ,2 ]
Clarot, Igor [4 ]
Boudier, Ariane [4 ]
Chen, Zilin [1 ,2 ,3 ]
机构
[1] Wuhan Univ, Hubei Prov Engn & Technol Res Ctr Fluorinated Pha, Key Lab Combinatorial Biosynth & Drug Discovery, Minist Educ, Wuhan 430071, Peoples R China
[2] Wuhan Univ, Sch Pharmaceut Sci, Wuhan 430071, Peoples R China
[3] Chinese Acad Sci, State Key Lab Transducer Technol, Beijing 100080, Peoples R China
[4] Univ Lorraine, CITHEFOR, F-54000 Nancy, France
基金
中国国家自然科学基金;
关键词
IN-SITU SYNTHESIS; SEPARATION; IMMOBILIZATION; GRAPHENE; POLYMER;
D O I
10.1039/d1an01402a
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Covalent organic frameworks (COFs) are a class of porous materials with high surface area, high porosity, good stability and tunable structure that have been widely used in the separation area. In this work, we have proposed the in situ synthesis of a novel COF composed of 4,4 ',4 ''-(1,3,5-triazine-2,4,6-triyl)trianiline (Tz) and 1,4-dihydroxyterephthalaldehyde (Da) onto the capillary inner surface for electrochromatographic separation. Fourier transform infrared (FT-IR) spectroscopy, elemental analysis (EA) and scanning electron microscopy (SEM) have facilitated the characterization of the prepared capillary columns. The COF (TzDa) modified OT-CEC column exhibited satisfactory separation selectivity towards neutral compounds (such as chlorobenzenes and alkylbenzenes), acidic and basic compounds (such as phenols and anilines), food additives (vanillin and its analogues) and small biomolecules (such as amino acids and polypeptides). Furthermore, the TzDa modified capillary was quite stable and reproducible. The relative standard deviations for retention times of the test analytes (alkylbenzenes) were as follows: for intra-day (n = 3) runs (<= 1.74%), inter-day (n = 3) runs (<= 2.25%) and between columns (n = 3) (<= 4.83%). This new type of COF-based stationary phase has tremendous potential in separation science.
引用
收藏
页码:6643 / 6649
页数:7
相关论文
共 33 条
[1]   Computational Selection of High-Performing Covalent Organic Frameworks for Adsorption and Membrane-Based CO2/H2 Separation [J].
Aksu, Gokhan Onder ;
Daglar, Hilal ;
Altintas, Cigdem ;
Keskin, Seda .
JOURNAL OF PHYSICAL CHEMISTRY C, 2020, 124 (41) :22577-22590
[2]   An immobilized carboxyl containing metal-organic framework-5 stationary phase for open-tubular capillary electrochromatography [J].
Bao, Tao ;
Tang, Pingxiu ;
Mao, Zhenkun ;
Chen, Zilin .
TALANTA, 2016, 154 :360-366
[3]   Polydopamine-supported immobilization of covalent-organic framework-5 in capillary as stationary phase for electrochromatographic separation [J].
Bao, Tao ;
Tang, Pingxiu ;
Kong, Deying ;
Mao, Zhenkun ;
Chen, Zilin .
JOURNAL OF CHROMATOGRAPHY A, 2016, 1445 :140-148
[4]   Growth of metal-organic framework HKUST-1 in capillary using liquid-phase epitaxy for open-tubular capillary electrochromatography and capillary liquid chromatography [J].
Bao, Tao ;
Zhang, Juan ;
Zhang, Wenpeng ;
Chen, Zilin .
JOURNAL OF CHROMATOGRAPHY A, 2015, 1381 :239-246
[5]   Storage of Hydrogen, Methane, and Carbon Dioxide in Highly Porous Covalent Organic Frameworks for Clean Energy Applications [J].
Furukawa, Hiroyasu ;
Yaghi, Omar M. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (25) :8875-8883
[6]   Chiral 3D Covalent Organic Frameworks for High Performance Liquid Chromatographic Enantioseparation [J].
Hang, Xing ;
Huang, Jinjing ;
Yuan, Chen ;
Liu, Yan ;
Cui, Yong .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 140 (03) :892-895
[7]   Two-dimensional covalent organic frameworks as self-template derived nitrogen-doped carbon nanosheets for eco-friendly metal-free catalysis [J].
Hu, Xiwei ;
Long, Yu ;
Fan, Mengying ;
Yuan, Man ;
Zhao, Hong ;
Ma, Jiantai ;
Dong, Zhengping .
APPLIED CATALYSIS B-ENVIRONMENTAL, 2019, 244 :25-35
[8]   Covalent organic framework TpPa-1 as stationary phase for capillary electrochromatographic separation of drugs and food additives [J].
Kong, Deying ;
Chen, Zilin .
ELECTROPHORESIS, 2018, 39 (22) :2912-2918
[9]   In situ synthesis of the imine-based covalent organic framework LZU1 on the inner walls of capillaries for electrochromatographic separation of nonsteroidal drugs and amino acids [J].
Kong, Deying ;
Bao, Tao ;
Chen, Zilin .
MICROCHIMICA ACTA, 2017, 184 (04) :1169-1176
[10]   Preparation and evaluation of a novel N-benzyl-phenethylamino-β-cyclodextrin-bonded chiral stationary phase for HPLC [J].
Li, Liang ;
Cheng, Biaoping ;
Zhou, Rendan ;
Cao, Zhigang ;
Zeng, Chun ;
Li, Laisheng .
TALANTA, 2017, 174 :179-191