Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review

被引：6
|
作者：
Luo, Lijuan [1 ]
Shen, Nan [1 ]
Chen, Wenjuan [1 ]
Luo, Chengjuan [2 ]
Huang, Xiaohang [2 ]
Jiang, Yuelian [3 ]
Cao, Qing [1 ]
机构：
[1] Shanghai Jiao Tong Univ, Shanghai Childrens Med Ctr, Sch Med, Dept Infect Dis, Shanghai, Peoples R China
[2] Shanghai Jiao Tong Univ, Shanghai Childrens Med Ctr, Sch Med, Dept Hematol & Oncol, Shanghai, Peoples R China
[3] Shanghai Jiao Tong Univ, Shanghai Childrens Med Ctr, Sch Med, Dept Pharm, Shanghai, Peoples R China
来源：
PEDIATRIC INVESTIGATION | 2021年 / 5卷 / 03期
关键词：
Toxoplasmosis; Hematopoietic stem cell transplantation; Pediatric; PROPHYLAXIS; DIAGNOSIS; FORGET;
D O I：
10.1002/ped4.12290
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Introduction Toxoplasmosis is a life-threatening complication after hematopoietic stem cell transplantation (HSCT). However, for several reasons, clinicians know little about Toxoplasma infection. Case presentation We report a case of toxoplasmosis that was diagnosed by bone marrow smear and metagenomic next-generation sequencing (mNGS) after HSCT in a boy. Additionally, we summarize the characteristics of toxoplasmosis after pediatric HSCT reported in the literature published in PubMed. Conclusion Clinicians should increase their awareness of toxoplasmosis in children after HSCT and implement pre-transplant screening and post-transplant monitoring and prevention in future according to the national conditions of our country.
引用
收藏
页码：239 / 243
页数：5
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