Surface modified halloysite nanotubes with different lumen diameters as drug carriers for cancer therapy

被引：21

作者：

Liao, Juan ^{[1
]}

Wang, Dongyue ^{[1
]}

Tang, Aidong ^{[2
]}

Fu, Liangjie ^{[1
,3
,4
]}

Ouyang, Jing ^{[1
,4
]}

Yang, Huaming ^{[1
,3
,4
]}

机构：

[1] Cent South Univ, Sch Minerals Proc & Bioengn, Hunan Key Lab Mineral Mat & Applicat, Changsha 410083, Peoples R China

[2] Cent South Univ, Sch Chem & Chem Engn, Changsha 410083, Peoples R China

[3] China Univ Geosci, Engn Res Ctr Nanogeomat, Minist Educ, Wuhan 430074, Peoples R China

[4] Cent South Univ, Hunan Int Joint Lab Mineral Mat, Changsha 410083, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2021年 / 57卷 / 74期

基金：

中国国家自然科学基金;

关键词：

CLAY NANOTUBES; DELIVERY; NANOPARTICLES;

D O I：

10.1039/d1cc01879e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Paclitaxel (PTX) is successfully loaded by surface modification of distearoyl phosphoethanolamine (DSPE) on halloysite nanotubes (HNTs) with different inner lumen diameters. Drug loading of DSPE-HNTs-PTX attains 18.44% of DSPE content with a nearly complete release (near 100%) achieved. The anticancer efficacy (cell viability less than 52%) of DSPE-HNTs15-PTX increased and is attributed to the lower interfacial energy both inside and outside the tubes that improves tube loading.

引用

页码：9470 / 9473

页数：4

共 50 条

[41] Bacteria and bacterial derivatives as drug carriers for cancer therapy
Cao, Zhenping
Liu, Jinyao
JOURNAL OF CONTROLLED RELEASE, 2020, 326 : 396 - 407
[42] Bacteria and bacterial derivatives as drug carriers for cancer therapy
Cao, Zhenping
Liu, Jinyao
Journal of Controlled Release, 2020, 326 : 396 - 407
[43] Exosomes as Drug Carriers in Anti-Cancer Therapy
Chen, Lan
Wang, Li
Zhu, Lingling
Xu, Zihan
Liu, Yanyang
Li, Zhixi
Zhou, Jin
Luo, Feng
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 10
[44] Effect of Surface Modified Halloysite Nanotubes (mHNTs) on the Mechanical Properties and Swelling Resistance of EPDM/NBR Nanocomposites
Sundar, R.
Mohan, S. Krishna
Vishvanathperumal, S.
POLYMER-KOREA, 2022, 46 (06) : 728 - 743
[45] Surface-modified halloysite nanotubes reinforced poly(lactic acid) for use in biodegradable coronary stents
Chen, Yuanyuan
Murphy, Alan
Scholz, Dimitri
Geever, Luke M.
Lyons, John G.
Devine, Declan M.
JOURNAL OF APPLIED POLYMER SCIENCE, 2018, 135 (30)
[46] Hyaluronic acid-modified multiwalled carbon nanotubes as drug delivery carrier for targeted cancer therapy
Cao, Xueyan
Tao, Lei
Wen, Shihui
Hou, Wenxiu
Shi, Xiangyang
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 247
[47] Carbon-based drug delivery carriers for cancer therapy
Lim, Dong-Jin
Sim, Myeongbu
Oh, Leeseul
Lim, Kyunghee
Park, Hansoo
ARCHIVES OF PHARMACAL RESEARCH, 2014, 37 (01) : 43 - 52
[48] Cyclodextrin-functionalized polymers as drug carriers for cancer therapy
Wei, Hua
Yu, Cui-yun
BIOMATERIALS SCIENCE, 2015, 3 (07) : 1050 - 1060
[49] Carbon-based drug delivery carriers for cancer therapy
Dong-Jin Lim
Myeongbu Sim
Leeseul Oh
Kyunghee Lim
Hansoo Park
Archives of Pharmacal Research, 2014, 37 : 43 - 52
[50] Design of an "Active Defense" System as Drug Carriers for Cancer Therapy
Zhang, Jing
Xu, Xiao-Ding
Liu, Yun
Liu, Chen-Wei
Chen, Xiu-Hong
Li, Cao
Zhuo, Ren-Xi
Zhang, Xian-Zheng
ADVANCED FUNCTIONAL MATERIALS, 2012, 22 (08) : 1704 - 1710

← 1 2 3 4 5 →