Surface microstructure and cell compatibility of calcium silicate and calcium phosphate composite coatings on Mg-Zn-Mn-Ca alloys for biomedical application

被引：43
作者：
Du, Hui [1 ]
Wei, Zunjie [1 ]
Wang, Hongwei [1 ]
Zhang, Erlin [2 ]
Zuo, Lin [3 ]
Du, Lianping [4 ]
机构：
[1] Harbin Inst Technol, Sch Mat Sci & Engn, Harbin 150001, Peoples R China
[2] Jiamusi Univ, Sch Mat & Engn, Jiamusi 154007, Peoples R China
[3] China Med Univ, Shenyang 110001, Peoples R China
[4] Weigao Grp, Weihai 264209, Peoples R China
来源：
COLLOIDS AND SURFACES B-BIOINTERFACES | 2011年 / 83卷 / 01期
关键词：
Osteoblast; Cytocompatibility; Bioactivity; Proliferation; Mg-Zn-Mn-Ca alloy; IN-VIVO CORROSION; SUBSTITUTED HYDROXYAPATITE; MAGNESIUM ALLOYS; VITRO; ELECTRODEPOSITION; DIFFERENTIATION; BIODEGRADATION; PROLIFERATION; OSTEOBLASTS; DISSOLUTION;
D O I：
10.1016/j.colsurfb.2010.11.003
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
A calcium silicate and calcium phosphate (CaSiO3/CaHPO4 center dot 2H(2)O) composite coating was applied by a chemical reaction to Mg-Zn-Mn-Ca alloy to improve its biocompatiblity. The surface microstructure was observed by scanning electronic microscopy (SEM) and the surface bioactivity was assessed by a cell interaction experiment. SEM observation showed that a microporous layer was formed on the surface of Mg-Zn-Mn-Ca alloy. It was shown by XRD that the reaction layer was mainly composed of CaHPO4 center dot 2H(2)O and a small amount of CaSiO3. In vitro cell experiments indicated that osteoblasts showed good adhesion, high growth rates and proliferation characteristics on the coated Mg-Zn-Mn-Ca alloy, indicating that the surface cytocompatibility of Mg-Zn-Mn-Ca alloy was significantly improved by the calcium phosphate coating. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码：96 / 102
页数：7
相关论文
共 44 条
[1]   A comparative study of biphasic calcium phosphate ceramics for human mesenchymal stem-cell-induced bone formation [J].
Arinzeh, TL ;
Tran, T ;
Mcalary, J ;
Daculsi, G .
BIOMATERIALS, 2005, 26 (17) :3631-3638
[2]   Biomimetic synthesis of carbonated hydroxyapatite thin films [J].
Boanini, E ;
Bigi, A .
THIN SOLID FILMS, 2006, 497 (1-2) :53-57
[3]  
Bowers K T, 1992, Int J Oral Maxillofac Implants, V7, P302
[4]   SILICON . A POSSIBLE FACTOR IN BONE CALCIFICATION [J].
CARLISLE, EM .
SCIENCE, 1970, 167 (3916) :279-&
[5]  
CPAT K, 1984, J BIOMED MATER RES, V18, P845
[6]   Morphological and structural study of pseudowollastonite implants in bone [J].
De Aza, P.N. ;
Luklinska, Z.B. ;
Martinez, A. ;
Anseau, M.R. ;
Guitian, F. ;
De Aza, S. ;
De Aza, S. .
Journal of Microscopy, 2000, 197 (01) :60-67
[7]  
Di Mario Carlo, 2004, J Interv Cardiol, V17, P391, DOI 10.1111/j.1540-8183.2004.04081.x
[8]   The preparation, cytocompatibility, and in vitro biodegradation study of pure β-TCP on magnesium [J].
Geng, F. ;
Tan, L. L. ;
Jin, X. X. ;
Yang, J. Y. ;
Yang, K. .
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2009, 20 (05) :1149-1157
[9]  
GIBSON IR, 1999, P 12 INT S CER MED N, P191
[10]  
HAO HP, 2000, BIOL EVALUATION NORM, pCH7
12345