Surface microstructure and cell compatibility of calcium silicate and calcium phosphate composite coatings on Mg-Zn-Mn-Ca alloys for biomedical application

被引：42
作者：
Du, Hui [1 ]
Wei, Zunjie [1 ]
Wang, Hongwei [1 ]
Zhang, Erlin [2 ]
Zuo, Lin [3 ]
Du, Lianping [4 ]
机构：
[1] Harbin Inst Technol, Sch Mat Sci & Engn, Harbin 150001, Peoples R China
[2] Jiamusi Univ, Sch Mat & Engn, Jiamusi 154007, Peoples R China
[3] China Med Univ, Shenyang 110001, Peoples R China
[4] Weigao Grp, Weihai 264209, Peoples R China
来源：
COLLOIDS AND SURFACES B-BIOINTERFACES | 2011年 / 83卷 / 01期
关键词：
Osteoblast; Cytocompatibility; Bioactivity; Proliferation; Mg-Zn-Mn-Ca alloy; IN-VIVO CORROSION; SUBSTITUTED HYDROXYAPATITE; MAGNESIUM ALLOYS; VITRO; ELECTRODEPOSITION; DIFFERENTIATION; BIODEGRADATION; PROLIFERATION; OSTEOBLASTS; DISSOLUTION;
D O I：
10.1016/j.colsurfb.2010.11.003
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
A calcium silicate and calcium phosphate (CaSiO3/CaHPO4 center dot 2H(2)O) composite coating was applied by a chemical reaction to Mg-Zn-Mn-Ca alloy to improve its biocompatiblity. The surface microstructure was observed by scanning electronic microscopy (SEM) and the surface bioactivity was assessed by a cell interaction experiment. SEM observation showed that a microporous layer was formed on the surface of Mg-Zn-Mn-Ca alloy. It was shown by XRD that the reaction layer was mainly composed of CaHPO4 center dot 2H(2)O and a small amount of CaSiO3. In vitro cell experiments indicated that osteoblasts showed good adhesion, high growth rates and proliferation characteristics on the coated Mg-Zn-Mn-Ca alloy, indicating that the surface cytocompatibility of Mg-Zn-Mn-Ca alloy was significantly improved by the calcium phosphate coating. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码：96 / 102
页数：7
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