Iridoids from Gardenia jasminoides

被引:25
|
作者
Ragasa, Consolacion Y.
Pimenta, Leslie Elline N.
Rideout, John A.
机构
[1] De La Salle Univ, Dept Chem, Manila 1004, Philippines
[2] De La Salle Univ, Ctr Nat Sci & Ecol Res, Manila 1004, Philippines
[3] Univ Cent Queensland, Sch Chem & Biomed Sci, Queensland 4701, Australia
关键词
Gardenia jasminoides ellis; rubiaceae; iridoids;
D O I
10.1080/14786410701589998
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The dichloromethane extract of the air- dried flowers of Gardenia jasminoides Ellis. afforded a new iridoid natural product ( 1), and a diastereomeric mixture of two new iridoids ( 2a and 2b) in a 2 : 1 ratio. Their structures were elucidated by extensive 1D and 2D NMR spectroscopy. Antimicrobial tests on 1 indicated that it was moderately active against Candida albicans; slightly active against E. coli, Pseudomonas aeruginosa, Staphylococcus. aureus, and Trichophyton mentagrophytes; and inactive against Bacillus subtilis and Aspergillus niger.
引用
收藏
页码:1078 / 1084
页数:7
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