共 4 条
[1]
Discovery of A Novel Her-1/Her-2 Dual Tyrosine Kinase Inhibitor for the Treatment of Her-1 Selective Inhibitor-Resistant Non-small Cell Lung Cancer
[J].
Cha, Mi Young
;
Lee, Kwang-Ok
;
Kim, Jong Woo
;
Lee, Chang Gon
;
Song, Ji Yeon
;
Kim, Young Hoon
;
Lee, Gwan Sun
;
Park, Seung Bum
;
Kim, Maeng Sup
.
JOURNAL OF MEDICINAL CHEMISTRY,
2009, 52 (21)
:6880-6888

Cha, Mi Young
论文数: 0 引用数: 0
h-index: 0
机构:
Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea
Seoul Natl Univ, Dept Chem, Seoul 151747, South Korea Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea

Lee, Kwang-Ok
论文数: 0 引用数: 0
h-index: 0
机构:
Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea

Kim, Jong Woo
论文数: 0 引用数: 0
h-index: 0
机构:
Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea

Lee, Chang Gon
论文数: 0 引用数: 0
h-index: 0
机构:
Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea

Song, Ji Yeon
论文数: 0 引用数: 0
h-index: 0
机构:
Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea

Kim, Young Hoon
论文数: 0 引用数: 0
h-index: 0
机构:
Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea

Lee, Gwan Sun
论文数: 0 引用数: 0
h-index: 0
机构:
Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea

Park, Seung Bum
论文数: 0 引用数: 0
h-index: 0
机构:
Seoul Natl Univ, Dept Chem, Seoul 151747, South Korea
Seoul Natl Univ, Dept Biophys & Chem Biol, Seoul 151747, South Korea Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea

Kim, Maeng Sup
论文数: 0 引用数: 0
h-index: 0
机构:
Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea Hanmi Res Ctr, Dept Drug Discovery, Hwaseong 445813, Gyeonggi Do, South Korea
[2]
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
[J].
Engelman, Jeffrey A.
;
Zejnullahu, Kreshnik
;
Mitsudomi, Tetsuya
;
Song, Youngchul
;
Hyland, Courtney
;
Park, Joon Oh
;
Lindeman, Neal
;
Gale, Christopher-Michael
;
Zhao, Xiaojun
;
Christensen, James
;
Kosaka, Takayuki
;
Holmes, Alison J.
;
Rogers, Andrew M.
;
Cappuzzo, Federico
;
Mok, Tony
;
Lee, Charles
;
Johnson, Bruce E.
;
Cantley, Lewis C.
;
Janne, Pasi A.
.
SCIENCE,
2007, 316 (5827)
:1039-1043

Engelman, Jeffrey A.
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Zejnullahu, Kreshnik
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Mitsudomi, Tetsuya
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Song, Youngchul
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Hyland, Courtney
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Park, Joon Oh
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Lindeman, Neal
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Gale, Christopher-Michael
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Zhao, Xiaojun
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Christensen, James
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Kosaka, Takayuki
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Holmes, Alison J.
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Rogers, Andrew M.
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Cappuzzo, Federico
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Mok, Tony
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Lee, Charles
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Johnson, Bruce E.
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Cantley, Lewis C.
论文数: 0 引用数: 0
h-index: 0
机构: Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

Janne, Pasi A.
论文数: 0 引用数: 0
h-index: 0
机构:
Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA
[3]
Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib
[J].
Kwak, EL
;
Sordella, R
;
Bell, DW
;
Godin-Heymann, N
;
Okimoto, RA
;
Brannigan, BW
;
Harris, PL
;
Driscoll, DR
;
Fidias, P
;
Lynch, TJ
;
Rabindran, SK
;
McGinnis, JP
;
Wissner, A
;
Sharma, SV
;
Isselbacher, KJ
;
Settleman, J
;
Haber, DA
.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,
2005, 102 (21)
:7665-7670

Kwak, EL
论文数: 0 引用数: 0
h-index: 0
机构: Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA

Sordella, R
论文数: 0 引用数: 0
h-index: 0
机构: Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA

Bell, DW
论文数: 0 引用数: 0
h-index: 0
机构: Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA

Godin-Heymann, N
论文数: 0 引用数: 0
h-index: 0
机构: Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA

Okimoto, RA
论文数: 0 引用数: 0
h-index: 0
机构: Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA

Brannigan, BW
论文数: 0 引用数: 0
h-index: 0
机构: Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA

Harris, PL
论文数: 0 引用数: 0
h-index: 0
机构: Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA

Driscoll, DR
论文数: 0 引用数: 0
h-index: 0
机构: Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA

Fidias, P
论文数: 0 引用数: 0
h-index: 0
机构: Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA

Lynch, TJ
论文数: 0 引用数: 0
h-index: 0
机构: Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA

Rabindran, SK
论文数: 0 引用数: 0
h-index: 0
机构: Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA

McGinnis, JP
论文数: 0 引用数: 0
h-index: 0
机构: Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA

Wissner, A
论文数: 0 引用数: 0
h-index: 0
机构: Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA

Sharma, SV
论文数: 0 引用数: 0
h-index: 0
机构: Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA

Isselbacher, KJ
论文数: 0 引用数: 0
h-index: 0
机构: Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA

Settleman, J
论文数: 0 引用数: 0
h-index: 0
机构:
Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA

Haber, DA
论文数: 0 引用数: 0
h-index: 0
机构: Massachusetts Gen Hosp, Ctr Canc, Med Oncol Unit, Charlestown, MA 02129 USA
[4]
HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors
[J].
Wang, Shizhen Emily
;
Narasanna, Archana
;
Perez-Torres, Marianela
;
Xiang, Bin
;
Wu, Frederick Y.
;
Yang, Seungchan
;
Carpenter, Graham
;
Gazdar, Adi F.
;
Muthuswamy, Senthil K.
;
Arteaga, Carlos L.
.
CANCER CELL,
2006, 10 (01)
:25-38

Wang, Shizhen Emily
论文数: 0 引用数: 0
h-index: 0
机构: Vanderbilt Univ, Sch Med, Dept Canc Biol, Nashville, TN 37232 USA

Narasanna, Archana
论文数: 0 引用数: 0
h-index: 0
机构: Vanderbilt Univ, Sch Med, Dept Canc Biol, Nashville, TN 37232 USA

Perez-Torres, Marianela
论文数: 0 引用数: 0
h-index: 0
机构: Vanderbilt Univ, Sch Med, Dept Canc Biol, Nashville, TN 37232 USA

Xiang, Bin
论文数: 0 引用数: 0
h-index: 0
机构: Vanderbilt Univ, Sch Med, Dept Canc Biol, Nashville, TN 37232 USA

Wu, Frederick Y.
论文数: 0 引用数: 0
h-index: 0
机构: Vanderbilt Univ, Sch Med, Dept Canc Biol, Nashville, TN 37232 USA

Yang, Seungchan
论文数: 0 引用数: 0
h-index: 0
机构: Vanderbilt Univ, Sch Med, Dept Canc Biol, Nashville, TN 37232 USA

Carpenter, Graham
论文数: 0 引用数: 0
h-index: 0
机构: Vanderbilt Univ, Sch Med, Dept Canc Biol, Nashville, TN 37232 USA

Gazdar, Adi F.
论文数: 0 引用数: 0
h-index: 0
机构: Vanderbilt Univ, Sch Med, Dept Canc Biol, Nashville, TN 37232 USA

Muthuswamy, Senthil K.
论文数: 0 引用数: 0
h-index: 0
机构: Vanderbilt Univ, Sch Med, Dept Canc Biol, Nashville, TN 37232 USA

Arteaga, Carlos L.
论文数: 0 引用数: 0
h-index: 0
机构:
Vanderbilt Univ, Sch Med, Dept Canc Biol, Nashville, TN 37232 USA Vanderbilt Univ, Sch Med, Dept Canc Biol, Nashville, TN 37232 USA