Oncologic and functional outcomes of transoral CO2 laser cordectomy for early glottic cancer

被引:10
作者
del Mundo, Daryl Anne A. [1 ,3 ,4 ]
Morimoto, Koichi [1 ]
Masuda, Kuriko [5 ]
Iwaki, Shinobu [1 ]
Furukawa, Tatsuya [1 ]
Teshima, Masanori [1 ]
Shinomiya, Hirotaka [1 ]
Miyawaki, Daisuke [2 ]
Otsuki, Naoki [1 ]
Sasaki, Ryohei [2 ]
Nibu, Ken-ichi [1 ]
机构
[1] Kobe Univ, Dept Otolaryngol Head & Neck Surg, Grad Sch Med, Kobe, Hyogo, Japan
[2] Kobe Univ, Div Radiat Oncol, Grad Sch Med, Kobe, Hyogo, Japan
[3] Univ Philippines Manila, Dept Otorhinolaryngol, Manila, Philippines
[4] Philippine Gen Hosp, Manila, Philippines
[5] Canadian Acad, Kobe, Hyogo, Japan
关键词
Transoral CO2 laser cordectomy; Early glottic cancer; LASER-SURGERY; ENDOSCOPIC CORDECTOMY; VOICE; RADIOTHERAPY; CLASSIFICATION; MICROSURGERY; COMMITTEE; PROPOSAL;
D O I
10.1016/j.anl.2019.08.005
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Objective: To investigate the oncological and functional outcomes of the patients treated with transoral CO2 laser cordectomy for early glottic cancer. Patients and methods: Fifty-five consecutive patients who underwent CO2 laser cordectomy for early glottic cancer were retrospectively reviewed. Results: Overall survival, larynx preservation, and relapse free local control rates were 96%, 100%, and 91%, respectively. Five patients with local recurrences were salvaged with re-cordectomy and/or radiotherapy. In type I cordectomy, VHI-10 consistently improved during postoperative course and VHI-10 at postoperative 12 months was significantly better than preoperative value (2.3 vs. 9.4, p = 0.02). Perceptual grading, MPT, MFR and AC/DC also improved and were better than preoperative values. In type III cordectomy, shimmer at 12 months after cordectomy was significantly better than preoperative value (14.7 vs. 9.3, p = 0.007). Conclusions: These results further support the rationale of CO2 cordectomy as initial and salvage surgery for early glottic cancer. (C) 2019 Published by Elsevier B.V.
引用
收藏
页码:276 / 281
页数:6
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