Upper urothelial tract high-grade carcinoma: comparison of urine cytology and DNA methylation analysis in urinary samples

被引:21
作者
Pierconti, Francesco [1 ]
Martini, Maurizio [1 ]
Fiorentino, Vincenzo [1 ]
Cenci, Tonia [1 ]
Racioppi, Marco [2 ]
Foschi, Nazario [2 ]
Di Gianfrancesco, Luca [2 ]
Sacco, Emilio [2 ]
Rossi, Ernesto [3 ]
Larocca, Luigi M. [1 ]
Bassi, Pier Francesco [2 ]
机构
[1] Univ Cattolica Del S Cuore, Fdn Policlin A Gemelli, Dept Pathol, Inst Pathol, I-00138 Rome, Italy
[2] Univ Cattolica Del S Cuore, Fdn Policlin A Gemelli, Dept Urol, Inst Urol, I-00138 Rome, Italy
[3] Univ Cattolica Del S Cuore, Fdn Policlin A Gemelli, Dept Oncol, I-00138 Rome, Italy
关键词
Upper urothelial tract carcinoma (UTUC); Methylation; Cytology; Bladder EpiCheck test; Ureteral biopsy; RADICAL NEPHROURETERECTOMY; CANCER; OUTCOMES; BIOPSY;
D O I
10.1016/j.humpath.2021.09.007
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
urinary samples may represent a valid tool in the diagnostic process of patients with suspected UTUC. In cases with a difficult clinical decision after upper urinary tract biopsy and cytology, the methylation test could assist in the clinical management of UTUC patients. (c) 2021 Elsevier Inc. All rights reserved.
引用
收藏
页码:42 / 48
页数:7
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