Synthesis of Polyhydroquinoline Derivatives Through the Hantzsch Four Component Using Iron (III) Phosphate as a Catalyst

被引：23

作者：

Behbahani, Farahnaz K. ^{[1
]}

Homafar, Maryam ^{[1
]}

机构：

[1] Islamic Azad Univ, Dept Chem, Karaj Branch, Sch Sci, Karaj, Iran

来源：

SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY | 2012年 / 42卷 / 02期

关键词：

catalyst; four components; iron (III) phosphate; polyhydroquinoline; synthesis; ONE-POT SYNTHESIS; SOLVENT-FREE CONDITIONS; MICROWAVE IRRADIATION; EFFICIENT SYNTHESIS; ANHYDROUS FEPO4; ONE-STEP; CONDENSATION; 4-COMPONENT; FACILE; 1,4-DIHYDROPYRIDINES;

D O I：

10.1080/15533174.2011.610020

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An efficient Hantzsch four-component condensation reaction for the synthesis of polyhydroquinoline derivatives was found to proceed in the presence of iron (III) phosphate in ethanol under reflux condition. The method is really simple and environmentally benign. The keys features of this protocol are the use of a heterogeneous and reusable catalyst, high yields of products, nontoxic solvent, and short reaction times from the principles of green chemistry point of view.

引用

页码：291 / 295

页数：5

共 32 条

[1]

[Anonymous], 2004, CFNP TAP REP FERR PH, P1

[2] One-step, synthesis of Hantzsch esters and polyhydroquinoline derivatives using new organocatalyst [J].

Baghbanian, Seyed Meysam ;

Khaksar, Samad ;

Vahdat, Seyed Mohammad ;

Farhang, Maryam ;

Tajbakhsh, Mahmood .

CHINESE CHEMICAL LETTERS, 2010, 21 (05) :563-567

[3]

Behbahani F.K., 2011, KOREAN J CHEM SOC, V55, P633

[4] CuSO4 • 5H2O: A NOVEL, GREEN, REUSABLE, AND ENVIRONMENTALLY FRIENDLY CATALYST FOR THE ONE-POT, FOUR-COMPONENT SYNTHESIS OF β-ACETAMIDO CARBONYL COMPOUNDS [J].

Behbahani, Farahnaz K. ;

Doragi, Neda ;

Heravi, Majid M. .

SYNTHETIC COMMUNICATIONS, 2012, 42 (05) :705-713

[5] An efficient synthesis of 2-arylbenzimidazoles from o-phenylenediamines and arylaldehydes catalyzed by Fe/CeO2-ZrO2 nano fine particles [J].

Behbahani, Farahnaz K. ;

Ziaei, Parisa ;

Fakhroueian, Zahra ;

Doragi, Neda .

MONATSHEFTE FUR CHEMIE, 2011, 142 (09) :901-906

[6]

Behbahani FK, 2011, LETT ORG CHEM, V8, P431

[7] ANHYDROUS FePO4: A GREEN AND COST-EFFECTIVE CATALYST FOR THE ONE-POT THREE COMPONENT SYNTHESIS OF 2, 4, 5-TRIARYLATED IMIDAZOLES [J].

Behbahani, Farahnaz K. ;

Yektanezhad, Talaye ;

Khorrami, Afshin R. .

HETEROCYCLES, 2010, 81 (10) :2313-2321

[8] Solid-phase synthesis of 4-aryl-1,4-dihydropyridines via the Hantzsch three component condensation [J].

Breitenbucher, JG ;

Figliozzi, G .

TETRAHEDRON LETTERS, 2000, 41 (22) :4311-4315

[9] Multicomponent Hantzsch cyclocondensation as a route to highly functionalized 2- and 4-dihydropyridylalanines, 2- and 4-pyridylalanines, and their N-oxides:: preparation via a polymer-assisted solution-phase approach [J].

Dondoni, A ;

Massi, A ;

Minghini, E ;

Bertolasi, V .

TETRAHEDRON, 2004, 60 (10) :2311-2326

[10] An efficient one-pot synthesis of polyhydroquinoline derivatives through the Hantzsch four component condensation [J].

Donelson, James L. ;

Gibbs, Richard A. ;

De, Surya K. .

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2006, 256 (1-2) :309-311

← 1 2 3 4 →