The MAPPER2 Database: a multi-genome catalog of putative transcription factor binding sites

被引：18
作者：
Riva, Alberto [1 ,2 ]
机构：
[1] Univ Florida, Dept Mol Genet & Microbiol, Gainesville, FL 32610 USA
[2] Univ Florida, Genet Inst, Gainesville, FL 32610 USA
来源：
NUCLEIC ACIDS RESEARCH | 2012年 / 40卷 / D1期
关键词：
D O I：
10.1093/nar/gkr1080
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The mapper(2) Database (http://genome.ufl.edu/mapperdb) is a component of mapper(2), a web-based system for the analysis of transcription factor binding sites in multiple genomes. The database contains predicted binding sites identified in the promoters of all human, mouse and Drosophila genes using 1017 probabilistic models representing over 600 different transcription factors. In this article we outline the current contents of the database and we describe its web-based user interface in detail. We then discuss ongoing work to extend the database contents to experimental data and to add analysis capabilities. Finally, we provide information about recent improvements to the hardware and software platform that mapper(2) is based on.
引用
收藏
页码：D155 / D161
页数：7
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