Case Report: Pure Red Cell Aplasia due to Angioimmunoblastic T-Cell Lymphoma

被引：2

作者：

Vitorino, Marina ^{[1
]}

Nunes, Filipa ^{[2
]}

Costa, Mariana ^{[2
]}

Porteiro, Beatriz ^{[2
]}

Borges, Alexys Reis ^{[2
]}

Machado, Joao ^{[2
]}

机构：

[1] Hosp Prof Doutor Fernando Fonseca, Dept Oncol, IC 19 Venteira, P-2720276 Amadora, Portugal

[2] Hosp Prof Doutor Fernando Fonseca, Dept Internal Med, Amadora, Portugal

来源：

CASE REPORTS IN ONCOLOGY | 2020年 / 13卷 / 01期

关键词：

Pure red cell aplasia; Angioimmunoblastic lymphoma; Anemia;

D O I：

10.1159/000505533

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Pure red cell aplasia (PRCA) is a rare bone marrow failure characterized by a progressive normocytic anemia and reticulocytopenia without leukopenia and thrombocytopenia. It can be associated with various hematological disorders but exceedingly rarely with angioimmunoblastic T-cell lymphoma (AITL). We report the case of a 72-year-old woman with PRCA associated with AITL. The patient presented with severe anemia (hemoglobin 2.6 g/dL) and a low reticulocyte count 0.7%. Direct and indirect Coombs tests were positive. A CT scan of the chest, abdomen, and pelvis revealed multiple lymphadenopathies. A cervical lymph node biopsy was compatible with AITL. A bone marrow biopsy showed medullary involvement by AITL and a severe erythroid hypoplasia with a myeloid:erythroid ratio of 19.70. The patient was started on CHOP and after 6 cycles the PET scan confirmed complete remission.

引用

页码：76 / 78

页数：3

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