Phenolic Compounds from Allium schoenoprasum, Tragopogon pratensis and Rumex acetosa and Their Antiproliferative Effects

被引：60

作者：

Kucekova, Zdenka ^{[1
]}

Mlcek, Jiri ^{[2
]}

Humpolicek, Petr ^{[1
,3
]}

Rop, Otakar ^{[2
]}

Valasek, Pavel ^{[3
]}

Saha, Petr ^{[3
]}

机构：

[1] Tomas Bata Univ Zlin, Fac Technol, Ctr Polymer, Zlin 76272, Czech Republic

[2] Tomas Bata Univ Zlin, Fac Technol, Dept Food Technol & Microbiol, Zlin 76272, Czech Republic

[3] Tomas Bata Univ Zlin, Ctr Polymer, Ctr Polymer Syst, Zlin 76005, Czech Republic

来源：

MOLECULES | 2011年 / 16卷 / 11期

关键词：

Allium schoenoprasum; Tragopogon pratensis; Rumex acetosa; proliferation; phenolic compounds; HaCaT; BLACK TEA POLYPHENOLS; RED WINE; CANCER CHEMOPREVENTION; FERULIC ACID; ANTIOXIDANT CAPACITY; MOLECULAR TARGETS; AROMATIC PLANTS; TUMOR GROWTH; IN-VITRO; RP-HPLC;

D O I：

10.3390/molecules16119207

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Experimental studies have shown that phenolic compounds have antiproliferative and tumour arresting effects. The aim of this original study was to investigate the content of phenolic compounds (PhC) in flowers of Allium schoenoprasum (chive), Tragopogon pratensis (meadow salsify) and Rumex acetosa (common sorrel) and their effect on proliferation of HaCaT cells. Antiproliferative effects were evaluated in vitro using the following concentrations of phenolic compounds in cultivation medium: 100, 75, 50 and 25 mu g/mL. Phenolic composition was also determined by HPLC. The results indicate that even low concentrations of these flowers' phenolic compounds inhibited cell proliferation significantly and the possible use of the studied herb's flowers as sources of active phenolic compounds for human nutrition.

引用

页码：9207 / 9217

页数：11

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