Cellulose-Based Nanofibril Composite Materials as a New Approach to Fight Bacterial Infections

被引:28
作者
Rashki, Somaye [1 ]
Shakour, Neda [2 ,3 ]
Yousefi, Zahra [4 ]
Rezaei, Marzieh [5 ]
Homayoonfal, Mina [6 ]
Khabazian, Ehsan [7 ]
Atyabi, Fatemeh [7 ,8 ]
Aslanbeigi, Fatemeh [9 ,10 ]
Lapavandani, Rouzita Safaei [11 ]
Mazaheri, Samaneh [12 ]
Hamblin, Michael R. [13 ]
Mirzaei, Hamed [6 ]
机构
[1] Kashan Univ Med Sci, Fac Med, Dept Microbiol & Immunol, Kashan, Iran
[2] Mashhad Univ Med Sci, Sch Pharm, Dept Med Chem, Mashhad, Razavi Khorasan, Iran
[3] Mashhad Univ Med Sci, Fac Med, Student Res Comm, Mashhad, Razavi Khorasan, Iran
[4] Shahroud Univ Med Sci, Sch Allied Med Sci, Shahroud, Iran
[5] Mashhad Univ Med Sci, Fac Med, Dept Med Biotechnol & Nanotechnol, Mashhad, Razavi Khorasan, Iran
[6] Kashan Univ Med Sci, Res Ctr Biochem & Nutr Metab Dis, Inst Basic Sci, Kashan, Iran
[7] Univ Tehran Med Sci, Fac Pharm, Dept Pharmaceut, Tehran, Iran
[8] Univ Tehran Med Sci, Fac Pharm, Nanotechnol Res Ctr, Tehran, Iran
[9] Kashan Univ Med Sci, Sch Med, Kashan, Iran
[10] Kashan Univ Med Sci, Student Res Comm, Kashan, Iran
[11] Shaheed Beheshti Univ Med Sci, Dept Gynecol & Obsteter, Tehran, Iran
[12] Univ Kashan, Fac Chem, Dept Analyt Chem, Kashan, Iran
[13] Univ Johannesburg, Fac Hlth Sci, Laser Res Ctr, Doornfontein, South Africa
关键词
cellulose; nanofibrils; antimicrobial activity; bacterial infections; nanotechnology; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; SALVADORA-PERSICA; MICROFIBRILLATED CELLULOSE; SILVER NANOPARTICLES; ANTI-BIOFILM; IN-VITRO; CHITOSAN; NANOCELLULOSE; HYDROGEL;
D O I
10.3389/fbioe.2021.732461
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Antibiotic resistant microorganisms have become an enormous global challenge, and are predicted to cause hundreds of millions of deaths. Therefore, the search for novel/ alternative antimicrobial agents is a grand global challenge. Cellulose is an abundant biopolymer with the advantages of low cost, biodegradability, and biocompatibility. With the recent growth of nanotechnology and nanomedicine, numerous researchers have investigated nanofibril cellulose to try to develop an anti-bacterial biomaterial. However, nanofibril cellulose has no inherent antibacterial activity, and therefore cannot be used on its own. To empower cellulose with anti-bacterial properties, new efficient nanomaterials have been designed based on cellulose-based nanofibrils as potential wound dressings, food packaging, and for other antibacterial applications. In this review we summarize reports concerning the therapeutic potential of cellulose-based nanofibrils against various bacterial infections
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页数:16
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