The widening role of statins: RAS signal transduction and drug-induced cytotoxicity in human leukemia: a commentary to 'interaction of cytosine arabinoside and lovastatin in human leukemia cells'

被引:3
作者
Braess, J [1 ]
Hiddemann, W [1 ]
机构
[1] Univ Munich, Univ Hosp Grosshadern, Dept Internal Med 3, Munich, Germany
关键词
D O I
10.1016/S0145-2126(01)00033-9
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
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页码:661 / 663
页数:3
相关论文
共 11 条
[1]   RAS and leukemia:: From basic mechanisms to gene-directed therapy [J].
Beaupre, DM ;
Kurzrock, R .
JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (03) :1071-1079
[2]   CGP57148B (STI-571) induces differentiation and apoptosis and sensitizes Bcr-Abl-positive human leukemia cells to apoptosis due to antileukemic drugs [J].
Fang, GF ;
Kim, CN ;
Perkins, CL ;
Ramadevi, N ;
Winton, E ;
Wittmann, S ;
Bhalla, KN .
BLOOD, 2000, 96 (06) :2246-2253
[3]   Creation of human tumour cells with defined genetic elements [J].
Hahn, WC ;
Counter, CM ;
Lundberg, AS ;
Beijersbergen, RL ;
Brooks, MW ;
Weinberg, RA .
NATURE, 1999, 400 (6743) :464-468
[4]   Interaction of cytosine arabinoside and lovastatin in human leukemia cells [J].
Holstein, SA ;
Hohl, RJ .
LEUKEMIA RESEARCH, 2001, 25 (08) :651-660
[5]   Protein kinase C targeting in antineoplastic treatment strategies [J].
Jarvis, WD ;
Grant, S .
INVESTIGATIONAL NEW DRUGS, 1999, 17 (03) :227-240
[6]   Evidence for involvement of mitogen-activated protein kinase, rather than stress-activated protein kinase, in potentiation of 1-β-D-arabinofuranosylcytosine-induced apoptosis by interruption of protein kinase C signaling [J].
Jarvis, WD ;
Fornari, FA ;
Tombes, RM ;
Erukulla, RK ;
Bittman, R ;
Schwartz, GK ;
Dent, P ;
Grant, S .
MOLECULAR PHARMACOLOGY, 1998, 54 (05) :844-856
[7]  
NEUBAUER A, 1994, BLOOD, V83, P1603
[8]   N-RAS MUTATIONS ARE ASSOCIATED WITH POOR-PROGNOSIS AND INCREASED RISK OF LEUKEMIA IN MYELODYSPLASTIC SYNDROME [J].
PAQUETTE, RL ;
LANDAW, EM ;
PIERRE, RV ;
KAHAN, J ;
LUBBERT, M ;
LAZCANO, O ;
ISAAC, G ;
MCCORMICK, F ;
KOEFFLER, HP .
BLOOD, 1993, 82 (02) :590-599
[9]  
RADICH JP, 1990, BLOOD, V76, P801
[10]   Ras protein farnesyltransferase: A strategic target for anticancer therapeutic development [J].
Rowinsky, EK ;
Windle, JJ ;
Von Hoff, DD .
JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (11) :3631-3652