Six-month smell and taste recovery rates in coronavirus disease 2019 patients: a prospective psychophysical study

被引：66

作者：

Petrocelli, M. ^{[1
,2
]}

Cutrupi, S. ^{[1
,3
]}

Salzano, G. ^{[1
,4
]}

Maglitto, F. ^{[1
,4
]}

Salzano, F. A. ^{[1
,5
]}

Lechien, J. R. ^{[6
,7
]}

Saussez, S. ^{[6
,7
]}

Boscolo-Rizzo, P. ^{[1
,8
]}

De Riu, G. ^{[1
,9
,10
]}

Vaira, L. A. ^{[1
,9
,11
]}

机构：

[1] Italian Res Grp Chemosensory Disorders Covid 19 P, Sassari, Italy

[2] AUSL Bologna, Bellaria & Maggiore Hosp, Maxillofaciai Surg Operat Unit, Bologna, Italy

[3] AUSL Bologna, Bellaria & Maggiore Hosp, Dent Operat Unit, Bologna, Italy

[4] Univ Hosp Naples Federico II, Maxillofacial Surg Unit, Naples, Italy

[5] Univ Salerno, Scuola Med Salernitan, Dept Med Surg & Dent, Otolaryngol Operat Unit, Salerno, Italy

[6] Int Federat Otorhinolaryngol Soc, Covid 19 Task Force Young Otolaryngologists, Paris, France

[7] Univ Mons, UMONS Res Inst Hlth Sci & Technol, Fac Med, Dept Human & Expt Oncol, Mons, Belgium

[8] Univ Trieste, Dept Med Surg & Hlth Sci, Trieste, Italy

[9] Univ Hosp Sassari, Maxillofacial Surg Operat Unit, Sassari, Italy

[10] Univ Sassari, Biomed Sci PhD Sch, Dept Med Surg & Expt Sci, Sassari, Italy

[11] Univ Sassari, Biomed Sci PhD Sch, Biomed Sci Dept, Sassari, Italy

来源：

JOURNAL OF LARYNGOLOGY AND OTOLOGY | 2021年 / 135卷 / 05期

关键词：

COVID-19; Olfaction Disorder; Taste; Smell; Anosmia; Ageusia; SARS-CoV-2; Coronavirus;

D O I：

10.1017/S002221512100116X

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Background The long-term recovery rate for coronavirus disease 2019 related chemosensory disturbances has not yet been clarified. Methods Olfactory and gustatory functions were assessed with psychophysical tests in patients in the first seven days from coronavirus disease 2019 onset and one, two, three and six months after the first evaluation. Results A total of 300 patients completed the study. The improvement in olfactory function was significant at the two-month follow up. At the end of the observation period, 27 per cent of the patients still experienced a persistent olfactory disturbance, including anosmia in 5 per cent of cases. As for taste, the improvement in the psychophysical scores was significant only between the baseline and the 30-day control. At the 6-month evaluation, 10 per cent of the patients presented with a persistent gustatory disturbance with an incidence of complete ageusia of 1 per cent. Conclusion Six months after the onset of coronavirus disease 2019, about 6 per cent of patients still had a severe persistent olfactory or gustatory disturbance.

引用

页码：436 / 441

页数：6

共 34 条

[1] Prevalence and Recovery From Olfactory and Gustatory Dysfunctions in Covid-19 Infection: A Prospective Multicenter Study [J].