OUTBREAK OF VIM-1-CARBAPENEMASE-PRODUCING ENTEROBACTER CLOACAE IN A PEDIATRIC INTENSIVE CARE UNIT

被引:34
|
作者
Oteo, Jesus [1 ]
Luis Hernandez-Almaraz, Jose [2 ]
Gil-Anton, Javier [3 ]
Vindel, Ana [1 ]
Fernandez, Sara [1 ]
Bautista, Veronica [1 ]
Campos, Jose [1 ,4 ]
机构
[1] Inst Salud Carlos III, Ctr Nacl Microbiol, Bacteriol Serv, Madrid 28220, Spain
[2] Hosp Cruces, Dept Microbiol, Baracaldo, Vizcaya, Spain
[3] PICU Hosp Cruces, Baracaldo, Vizcaya, Spain
[4] Consejo Super Invest Cient, Madrid, Spain
关键词
metallo-beta-lactamases; enterobacteria; VIM-1; outbreak; METALLO-BETA-LACTAMASES; PLASMIDS;
D O I
10.1097/INF.0b013e3181efaa2d
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Pediatric patients are rarely infected with metallo-beta-lactamase-producing Enterobacteriaceae. We describe 3 cases of children infected with VIM-1-producing clonal Enterobacter cloacae. Patients were treated with amikacin and cotrimoxazole. The bla(VIM-1) gene was carried into a class 1 integron and an IncHI2 incompatibility group plasmid. Emergence of pediatric infections caused by carbapenemases-producing Enterobacteriaceae is a critical issue as they are resistant to most beta-lactam antibiotics.
引用
收藏
页码:1144 / 1146
页数:3
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