Discovery of glpC, an organic solvent tolerance-related gene in Escherichia coli, using gene expression profiles from DNA microarrays

被引：33
作者：
Shimizu, K
Hayashi, S
Kako, T
Suzuki, M
Tsukagoshi, N
Doukyu, N
Kobayashi, T
Honda, H
机构：
[1] Nagoya Univ, Sch Engn, Dept Biotechnol, Chikusa Ku, Nagoya, Aichi 4648603, Japan
[2] Tokyo Inst Technol, Grad Sch Biosci & Biotechnol, Dept Biol Informat, Midori Ku, Yokohama, Kanagawa 227, Japan
来源：
APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2005年 / 71卷 / 02期
关键词：
D O I：
10.1128/AEM.71.2.1093-1096.2005
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Gene expression profiles were collected from Escherichia coli strains (OST3410, TK33, and TK31) before and after exposure to organic solvents, and the six genes that showed higher gene expression were selected. Among these genes, glpC encoding the anaerobic glycerol-3-phosphate dehydrogenase subunit C remarkably increased the organic solvent tolerance.
引用
收藏
页码：1093 / 1096
页数：4
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