Preparing for the long-haul: Autonomic complications of COVID-19

被引:53
作者
Larsen, Nicholas W. [1 ]
Stiles, Lauren E. [2 ]
Miglis, Mitchell G. [1 ]
机构
[1] Stanford Univ, Dept Neurol & Neurol Sci, Palo Alto, CA 94304 USA
[2] SUNY Stony Brook, Dept Neurol, Renaissance Sch Med, Stony Brook, NY 11794 USA
来源
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL | 2021年 / 235卷
关键词
COVID; Autonomic; POTS; Post-COVID; Post-acute COVID; Chronic; Dysautonomia; Long-haul COVID; CHRONIC-FATIGUE; TACHYCARDIA SYNDROME; PULMONARY-FUNCTION; DYSFUNCTION; SARS; AUTOANTIBODIES; SURVIVORS; SYMPTOMS; PROTEIN; ACE2;
D O I
10.1016/j.autneu.2021.102841
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
As global numbers of COVID-19 grow, chronic neurological symptoms, including those of autonomic dysfunction, are being reported with increasing frequency. Mounting evidence suggests that many patients experience chronic and sometimes debilitating symptoms long after their acute infectious period, leading to the new diagnostic category of post-acute COVID syndrome. Many symptoms of post-acute COVID syndrome appear autonomic in nature, suggesting that autonomic impairment may play a central role in the underlying pathophysiology. In this review, we discuss the autonomic symptoms and manifestations of post-acute COVID syndrome, potential mechanisms involved, and future directions for a better understanding of this novel condition.
引用
收藏
页数:9
相关论文
共 74 条
[1]   Covid-19 hyperinflammation and post-Covid-19 illness may be rooted in mast cell activation syndrome [J].
Afrin, Lawrence B. ;
Weinstock, Leonard B. ;
Molderings, Gerhard J. .
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2020, 100 :327-332
[2]   The Prevalence of Autoimmune Disorders in Women: A Narrative Review [J].
Angum, Fariha ;
Khan, Tahir ;
Kaler, Jasndeep ;
Siddiqui, Lena ;
Hussain, Azhar .
CUREUS JOURNAL OF MEDICAL SCIENCE, 2020, 12 (05)
[3]   Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: retrospective case series [J].
Argenziano, Michael G. ;
Bruce, Samuel L. ;
Slater, Cody L. ;
Tiao, Jonathan R. ;
Baldwin, Matthew R. ;
Barr, R. Graham ;
Chang, Bernard P. ;
Chau, Katherine H. ;
Choi, Justin J. ;
Gavin, Nicholas ;
Goyal, Parag ;
Mills, Angela M. ;
Patel, Ashmi A. ;
Romney, Marie-Laure S. ;
Safford, Monika M. ;
Schluger, Neil W. ;
Sengupta, Soumitra ;
Sobieszczyk, Magdalena E. ;
Zucker, Jason E. ;
Asadourian, Paul A. ;
Bell, Fletcher M. ;
Boyd, Rebekah ;
Cohen, Matthew F. ;
Colquhoun, MacAlistair I. ;
Colville, Lucy A. ;
de Jonge, Joseph H. ;
Dershowitz, Lyle B. ;
Dey, Shirin A. ;
Eiseman, Katherine A. ;
Girvin, Zachary P. ;
Goni, Daniella T. ;
Harb, Amro A. ;
Herzik, Nicholas ;
Householder, Sarah ;
Karaaslan, Lara E. ;
Lee, Heather ;
Lieberman, Evan ;
Ling, Andrew ;
Lu, Ree ;
Shou, Arthur Y. ;
Sisti, Alexander C. ;
Snow, Zachary E. ;
Sperring, Colin P. ;
Xiong, Yuqing ;
Zhou, Henry W. ;
Natarajan, Karthik ;
Hripcsak, George ;
Chen, Ruijun .
BMJ-BRITISH MEDICAL JOURNAL, 2020, 369
[4]  
Assaf G, 2020, What Does COVID-19 Recovery Actually Look Like? An Analysis of the Prolonged COVID-19 Symptoms Survey by Patient-Led Research Team
[5]  
Bishof K, 2020, POSTCOVID SYNDROME P
[6]   Postural tachycardia syndrome is not caused by deconditioning [J].
Blitshteyn, Svetlana ;
Fries, David .
PULMONARY CIRCULATION, 2016, 6 (03) :401-401
[7]   Syncope at SARS-CoV-2 onset [J].
Canetta, Ciro ;
Accordino, Silvia ;
Buscarini, Elisabetta ;
Benelli, Gianpaolo ;
La Piana, Giuseppe ;
Scartabellati, Alessandro ;
Vigano, Giovanni ;
Assandri, Roberto ;
Astengo, Alberto ;
Benzoni, Chiara ;
Gaudiano, Gianfranco ;
Cazzato, Daniele ;
Rossi, Davide Sebastiano ;
Usai, Susanna ;
Tramacere, Irene ;
Lauria, Giuseppe .
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL, 2020, 229
[8]   Persistent Symptoms in Patients After Acute COVID-19 [J].
Carfi, Angelo ;
Bernabei, Roberto ;
Landi, Francesco .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 324 (06) :603-605
[9]   SARS: Epidemiology [J].
Chan-Yeung, M ;
Xu, RH .
RESPIROLOGY, 2003, 8 :S9-S14
[10]  
Crameri Giovanni Andrea Gerardo, 2020, Euro Surveill, V25, DOI 10.2807/1560-7917.ES.2020.25.36.2001542