Generation of nanopores down to 10 nm for use in deep-nulling interferometry

被引:3
作者
Wehling, Axel [1 ]
Pohl, Wiebke H. [2 ]
Gerke, Birgit [1 ]
Kipp, Stephan [1 ]
Walla, Peter J. [1 ,2 ]
机构
[1] Tech Univ Carolo Wilhelmina Braunschweig, Inst Phys & Theoret Chem, Dept Biophys Chem, D-38106 Braunschweig, Germany
[2] Max Planck Inst Biophys Chem, Dept Spectroscopy & Photochem Kinet, D-37077 Gottingen, Germany
关键词
electron microscopy; interferometry; label-free; nanopores; single-molecule studies;
D O I
10.1002/cphc.200700606
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Scanning electron microscope images show that it is easy to generate nanopores on polycarbonate membranes with well-defined pore diameters by ion-track perforation and subsequent magnetron sputtering with metal. The size reduction of the nanopores during sputtering with gold is a linear function of time. Images of different angles and from the bottom side of the membrane show that the channels are the smallest very close to the surface of the metal layer, have a conelike shape, and reach about half as much into the polymer membranes as the metal-layer thickness. This topographical pore shape is ideal for use as optically coherent near-field sources in deep-nulling microscopy. We present the first results of significantly improved nulling stabilization in the presence (<2 nm optical pathway difference) and the absence (< 0.6 nm optical pathway difference) of the nanoapertures in the focal region of a deep-nulling microscope.
引用
收藏
页码:327 / 331
页数:5
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