Host glycolipids in SARS-CoV-2 entry

被引：9

作者：

Uraki, Ryuta ^{[1
]}

Kawaoka, Yoshihiro ^{[1
,2
,3
,4
]}

机构：

[1] Natl Ctr Global Hlth & Med Res Inst, Res Ctr Global Viral Dis, Tokyo, Japan

[2] Univ Tokyo, Inst Med Sci, Div Virol, Tokyo, Japan

[3] Univ Tokyo, Inst Med Sci, Dept Special Pathogens, Int Res Ctr Infect Dis, Tokyo, Japan

[4] Univ Wisconsin, Sch Vet Med, Dept Pathobiol Sci, Madison, WI 53706 USA

来源：

NATURE CHEMICAL BIOLOGY | 2022年 / 18卷 / 01期

关键词：

D O I：

10.1038/s41589-021-00923-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new study demonstrates that the receptor-binding domain of the SARS-CoV-2 spike protein binds to sialylated glycans, especially glycolipids, to facilitate viral entry, an insight that identifies new potential targets for SARS-CoV-2 interventions.

引用

页码：6 / 7

页数：2

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