Neuroimaging of deployment-associated traumatic brain injury (TBI) with a focus on mild TBI (mTBI) since 2009

被引:36
作者
Salat, David H. [1 ,2 ,3 ]
Robinson, Meghan E. [1 ,3 ,4 ]
Miller, Danielle R. [5 ,6 ]
Clark, Dustin C. [1 ]
McGlinchey, Regina E. [3 ,7 ,8 ]
机构
[1] VA Boston Healthcare Syst, Neuroimaging Res Vet NeRVe Ctr, 150 South Huntington Ave, Boston, MA 02130 USA
[2] Massachusetts Gen Hosp, Dept Radiol, Athinoula A Martinos Ctr Biomed Imaging, Charlestown, MA USA
[3] VA Boston Healthcare Syst, Translat Res Ctr TBI & Stress Disorders TRACTS, Boston, MA USA
[4] Boston Univ, Sch Med, Dept Neurol, Boston, MA 02118 USA
[5] VA Boston Healthcare Syst, Natl Ctr PTSD, Boston, MA USA
[6] Boston Univ, Sch Med, Dept Psychiat, Boston, MA 02118 USA
[7] Geriatr Res Educ & Clin Ctr, Boston, MA USA
[8] Harvard Med Sch, Dept Psychiat, Boston, MA USA
关键词
Cortical thickness; diffusion tensor imaging; DTI; EEG; ERP: positron emission tomography; FA tractography; fcMRI; FDG; fMRI; fractional anisotropy; functional connectivity; functional magnetic resonance imaging; Glasgow Coma Scale: concussion; magnetic resonance imaging; MEG; MRI; neuroimaging; PET; TBI; Traumatic brain injury; WHITE-MATTER ABNORMALITIES; POSTTRAUMATIC-STRESS-DISORDER; COMMON DATA ELEMENTS; FUNCTIONAL CONNECTIVITY; BLAST EXPOSURE; MILITARY PERSONNEL; CORTICAL THICKNESS; COMBAT VETERANS; ALZHEIMERS-DISEASE; ENDURING FREEDOM;
D O I
10.1080/02699052.2017.1327672
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Objectives:, A substantial body of recent research has aimed to better understand the clinical sequelae,of military trauma through the application of advanced brain imaging procedures in Veteran populations. The primary objective of this review was to highlight:a portion of these recent studies to demonstrate how imaging tools can be used to understand millitary-associated brain injury; Methods: We focus here on the phenomenon Of mild traumatic brain injury (mTBI) given its high prevalence in the Veteran population and,current recognition of the need to better understand, the clinical implications. of this trauma. ThiS is intended to provide readers with an initial exposure to the field of neuroimaging of. mTBI with A brief introduction to the concept of traumatic brain injury, followed by a summary-of the major imaging techniques that have been applied to the study of mTBI. Results: Taken together, the collection of studies reviewed demonstrates a clear role.-for neuroimaging towards understanding the various neural consequences of mTBI as well as the clinical complications of such brain changes. Conclusions This information must be considered-in the-larger context of research into mTBI, including the potentially unique nature of blast exposure and the long-term consequences of mTBI.
引用
收藏
页码:1204 / 1219
页数:16
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