Pneumocystis jirovecii pneumonia developed in a patient with rheumatoid arthritis after 14 weeks of iguratimod add-on to treatment with methotrexate and etanercept

被引：3
作者：
Arita, Yuki [1 ]
Taguchi, Hiroaki [2 ]
Kobayashi, Mari [1 ]
Tono, Toshihiro [2 ]
Ohsone, Yasuo [2 ]
Okano, Yutaka [2 ]
机构：
[1] Kawasaki Municipal Kawasaki Hosp, Dept Internal Med, Kawasaki, Kanagawa, Japan
[2] Kawasaki Municipal Kawasaki Hosp, Ctr Arthrit & Rheumat Dis, Kawasaki, Kanagawa, Japan
来源：
MODERN RHEUMATOLOGY | 2018年 / 28卷 / 06期
关键词：
Disease-modifying antirheumatic drug; Iguratimod; Pneumocystis jirovecii pneumonia; Rheumatoid arthritis; ANTIRHEUMATIC DRUG; DOUBLE-BLIND; THERAPY; EFFICACY;
D O I：
10.1080/14397595.2016.1181026
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 66-year-old woman who had rheumatoid arthritis and underwent a long-term treatment with methotrexate and etanercept developed Pneumocystis jirovecii pneumonia (PCP) 3 months after iguratimod add-on. Although most rheumatologists might have the impression that iguratimod has less toxicity and immunosuppressive effect compared with methotrexate and biologic disease-modifying antirheumatic drugs, this case suggests that iguratimod may increase the risk of PCP, especially in combination with other drugs.
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收藏
页码：1041 / 1043
页数：3
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