In Vitro Sensitivity and Resistance of 46 Leptospira Strains Isolated from Rats in the Philippines to 14 Antimicrobial Agents

被引：35

作者：

Chakraborty, Antara ^{[1
]}

Miyahara, Satoshi ^{[1
]}

Villanueva, Sharon Y. A. M. ^{[1
]}

Gloriani, Nina G. ^{[2
]}

Yoshida, Shin-ichi ^{[1
]}

机构：

[1] Kyushu Univ, Dept Bacteriol, Grad Sch Med Sci, Higashi Ku, Fukuoka 8128582, Japan

[2] Univ Philippines, Dept Med Microbiol, Coll Publ Hlth, Manila, Philippines

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2010年 / 54卷 / 12期

基金：

日本科学技术振兴机构;

关键词：

SELECTIVE ISOLATION; SUSCEPTIBILITIES; 5-FLUOROURACIL; DOXYCYCLINE; INTERROGANS; PENICILLIN; NEOMYCIN; EFFICACY;

D O I：

10.1128/AAC.00973-10

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The in vitro susceptibilities of 46 Leptospira isolates from rats to 14 antimicrobial agents were tested. All of the strains were found to be sensitive to ampicillin, cefotaxime, ciprofloxacin, norfloxacin, doxycycline, erythromycin, and streptomycin. In contrast, the tested isolates showed resistance to amphotericin B, 5-fluorouracil, fosfomycin, trimethoprim, sulfamethoxazole, neomycin, and vancomycin. These findings will help in selecting effective and ineffective antimicrobials for treatment of leptospirosis and for the development of new selective media, respectively.

引用

页码：5403 / 5405

页数：3

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