Phytochemistry, Pharmacology and Traditional Uses of Plants from the Genus Trachelospermum L.

被引:18
作者
Zhao, Zefeng [1 ]
He, Xirui [1 ,2 ]
Zhao, Yuhui [1 ]
Sun, Ying [1 ]
Chen, Xufei [1 ]
Cun, Ye [1 ]
Huang, Linhong [2 ]
Bai, Yajun [1 ,3 ]
Zheng, Xiaohui [1 ]
机构
[1] Northwest Univ, Key Lab Resource Biol & Biotechnol Western China, Minist Educ, 229 Taibai Rd, Xian 710069, Shaanxi, Peoples R China
[2] Xi An Jiao Tong Univ, Honghui Hosp, Xian 710054, Shaanxi, Peoples R China
[3] Northwest Univ, Coll Chem & Mat Sci, Xian 710069, Shaanxi, Peoples R China
基金
中国国家自然科学基金;
关键词
Trachelospermum; lignans; anti-inflammatory; analgesic; antitumor; review; ASIATICUM VAR-INTERMEDIUM; BONE CANCER PAIN; PREGNANE GLYCOSIDES; CARTHAMUS-TINCTORIUS; PHENOLIC-COMPOUNDS; LIGNAN GLYCOSIDES; JASMINOIDES; TRITERPENOIDS; CAULIS; LEAVES;
D O I
10.3390/molecules22091406
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This paper is intended to review advances in the botanical, phytochemical, traditional uses and pharmacological studies of the genus Trachelospermum. Until now, 138 chemical constituents have been isolated and characterized from these plants, particularly from T. asiaticum and T. jasminoides. Among these compounds, lignans, triterpenoids, and flavonoids are the major bioactive constituents. Studies have shown that plants from the genus Trachelospermum exhibit an extensive range of pharmacological properties both in vivo and in vitro, including anti-inflammatory, analgesic, antitumor, antiviral and antibacterial activities. In Traditional Chinese Medicine (TCM) culture, drugs that include T. jasminoides stems have been used to cure rheumatism, gonarthritis, backache and pharyngitis, although there are few reports concerning the clinical use and toxicity of these plants. Further attention should be paid to gathering information about their toxicology data, quality-control measures, and the clinical value of the active compounds from genus Trachelospermum.
引用
收藏
页数:17
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