Deriving blood stem cells from pluripotent stem cells for research and therapy

被引:5
作者
Daley, George Q.
Lux, Samuel E. [1 ,2 ,3 ,4 ]
机构
[1] Childrens Hosp, Stem Cell Transplantat Program, Philadelphia, PA USA
[2] Dana Farber Canc Inst, Boston, MA USA
[3] Harvard Univ, Sch Med, Cambridge, MA 02138 USA
[4] Howard Hughes Med Inst, Chevy Chase, MD USA
关键词
stem cells; induced pluripotent; hematopoietic stem cells (HSCs); transcription factors; stem cell models; NUCLEAR TRANSFER;
D O I
10.1016/j.beha.2014.10.013
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Embryonic stem cells and induced pluripotent stem cells offer promise for research and treatment of hematologic diseases. While broad clinical application in humans is still a distant prospect, there are promising near-term applications in transfusion of platelets and red blood cells. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码:293 / 297
页数:5
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