Morbidity, mortality and sleep-disordered breathing in community dwelling elderly

被引:157
|
作者
AncoliIsrael, S
Kripke, DF
Klauber, MR
Fell, R
Stepnowsky, C
Estline, E
Khazeni, N
Chinn, A
机构
[1] UNIV CALIF SAN DIEGO,DEPT PSYCHIAT,SAN DIEGO,CA 92103
[2] SAM & ROSE STEIN INST RES AGING,SAN DIEGO,CA
[3] UNIV CALIF SAN DIEGO,DEPT FAMILY & PREVENT MED,SAN DIEGO,CA 92103
关键词
sleep apnea; sleep-disordered breathing; elderly; mortality; natural history;
D O I
10.1093/sleep/19.4.277
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A population-based probability sample of elderly individuals (n = 426), who were originally studied between 1981 and 1986 (mean age at initial study was 72.5 years), were followed for mortality. Those with greater than or equal to 30 respiratory disturbances per hour of sleep had significantly shorter survival (p = 0.0034), but the respiratory disturbance index (RDI) was not an independent predictor of death. When Cox proportional hazards analysis was done, only age (the strongest predictor), cardiovascular disease and pulmonary disease were independent predictors of death. It may be that factors that are secondary to or associated with sleep-disordered breathing (SDB), such as cardiovascular or pulmonary disease, predispose these elderly to death.
引用
收藏
页码:277 / 282
页数:6
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