CRISPR-based pathogenic fungal genome editing for control of infection and disease

被引：4

作者：

Arazoe, Takayuki ^{[1
]}

机构：

[1] Tokyo Univ Sci, Fac Sci & Technol, Dept Appl Biol Sci, Noda, Chiba, Japan

来源：

REPROGRAMMING THE GENOME: APPLICATIONS OF CRISPR-CAS IN NON-MAMMALIAN SYSTEMS, PT A | 2021年 / 179卷

关键词：

TARGETED GENE REPLACEMENT; FILAMENTOUS FUNGI; WEB TOOL; SYSTEM; RNA; DNA; MUTAGENESIS; DISRUPTION; CHOPCHOP; STRAIN;

D O I：

10.1016/bs.pmbts.2020.12.016

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Fungi play important roles in many aspects of human life, such as in various food, beverage, agricultural, chemical, and pharmaceutical industries. Meanwhile, some fungal species cause several severe diseases in plants, humans and animals. Fungal and fungal-like diseases pose a severe threat to human health, food security, and ecosystem health worldwide. This chapter introduces CRISPR-based genome editing technologies for pathogenic fungi and their application in controlling fungal diseases.

引用

页码：161 / 196

页数：36

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