Identification and typing of the emerging pathogen Candida auris by matrix-assisted laser desorption ionisation time of flight mass spectrometry

被引：86

作者：

Girard, Victoria ^{[1
]}

Mailler, Sandrine ^{[1
]}

Chetry, Marion ^{[1
]}

Vidal, Celine ^{[2
]}

Durand, Geraldine ^{[1
]}

van Belkum, Alex ^{[1
]}

Colombo, Arnaldo L. ^{[3
]}

Hagen, Ferry ^{[4
]}

Meis, Jacques F. ^{[4
,5
]}

Chowdhary, Anuradha ^{[6
]}

机构：

[1] BioMerieux, R&D Microbiol, La Balme Les Grottes, France

[2] BioMerieux, R&D Biomath, Grenoble, France

[3] Univ Fed Sao Paulo, Lab Especial Micol, Escola Paulista Med, Sao Paulo, Brazil

[4] Canisius Wilhelmina Hosp, Dept Med Microbiol & Infect Dis, Nijmegen, Netherlands

[5] Radboud Univ Nijmegen, Dept Med Microbiol, Med Ctr, Nijmegen, Netherlands

[6] Univ Delhi, Dept Med Mycol, Vallabhbhai Patel Chest Inst, Delhi, India

来源：

MYCOSES | 2016年 / 59卷 / 08期

关键词：

Candida auris; matrix-assisted laser desorption ionisation-time of flight mass spectrometry; amplified fragment length polymorphism; MS VITEK; ANTIFUNGAL SUSCEPTIBILITY; BROTH MICRODILUTION; CLONAL STRAIN; HAEMULONII; YEASTS; ETEST; CLSI;

D O I：

10.1111/myc.12519

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Candida auris is an emerging antifungal resistant yeast species causing nosocomial and invasive infections, emphasising the need of improved diagnostics and epidemiological typing methods. We show that MALDI-TOF VITEK-MS followed by amplified length polymorphisms allows for accurate species identification and subsequent epidemiological characterisation of strains encountered during potential outbreaks.

引用

页码：535 / 538

页数：4

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