A novel naphthofluorescein-based probe for ultrasensitive point-of-care testing of zinc(II) ions and its bioimaging in living cells and zebrafishes

被引：13

作者：

Chen, Xingwei ^{[1
,2
]}

Xu, Jiajia ^{[1
,2
]}

Suo, Fengtai ^{[1
,2
]}

Yu, Changmin ^{[1
,2
]}

Zhang, Duoteng ^{[1
,2
]}

Chen, Jian ^{[5
]}

Wu, Qiong ^{[1
,2
]}

Jing, Su ^{[3
]}

Li, Lin ^{[1
,2
]}

Huang, Wei ^{[1
,2
,4
]}

机构：

[1] Nanjing Tech Univ, Nanjing Tech, KLOFE, 30 South Puzhu Rd, Nanjing 211816, Peoples R China

[2] Nanjing Tech Univ, Nanjing Tech, IAM, 30 South Puzhu Rd, Nanjing 211816, Peoples R China

[3] Nanjing Tech Univ, Sch Chem & Mol Engn, Nanjing 211816, Peoples R China

[4] Northwestern Polytech Univ, SIFE, 127 West Youyi Rd, Xian 710072, Peoples R China

[5] Hunan Univ Sci & Technol, Hunan Prov Key Lab Controllable Preparat & Funct, Xiangtan 411201, Hunan, Peoples R China

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2020年 / 229卷

基金：

中国国家自然科学基金;

关键词：

Zinc ions; Point-of-care testing; Paper-based devices; High-throughput; Imaging; FLUORESCENT-PROBE; FLUOROGENIC PROBE; IN-VITRO; PAPER; SENSOR; ZN2+; CYSTEINE; DEVICE;

D O I：

10.1016/j.saa.2019.117949

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

The combination of fluorescence method with paper-based diagnostic device is quite suitable in point-of-care testing (POCT). Herein, we designed a novel hybrid fluorescein-based probe ZN-2 and investigated its fluorescent properties thoroughly in the detection of Zn2+. In comparison with the fluorescein-based probe ZN-1, ZN-2 displayed better sensitivity, long-wavelength and faster response to Zn2+ within 20 min. Interestingly, we could achieve ultrasensitive, high-throughput and visual detection in the POCT analysis of Zn2+ by anchoring this probe ZN-2 on the paper-based device. This device with satisfied performance for Zn2+ detection was achieved in real samples including cytochylema, serum and lake water. Finally, the probe ZN-2 was further applied to visualize and monitor the level changes of Zn2+ in the living cells and zebrafishes. (C) 2018 Elsevier B.V. All rights reserved.

引用

页数：7

共 40 条

[1] A colorimetric paper sensor for citrate as biomarker for early stage detection of prostate cancer based on peroxidase-like activity of cysteine-capped gold nanoclusters [J].

Abarghoei, Shima ;

Fakhri, Neda ;

Borghei, Yasaman Sadat ;

Hosseini, Morteza ;

Ganjali, Mohammad Reza .

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2019, 210 :251-259

[2] A turn-on fluorescent sensor for Zn(II) based on fluorescein-coumarin conjugate [J].

An, Jun-mei ;

Yan, Mi-hui ;

Yang, Zheng-yin ;

Li, Tian-rong ;

Zhou, Qiao-xia .

DYES AND PIGMENTS, 2013, 99 (01) :1-5

[3] Cellphone-Based Hand-Held Microplate Reader for Point-of-Care Testing of Enzyme-Linked Immunosorbent Assays [J].

Berg, Brandon ;

Cortazar, Bingen ;

Tseng, Derek ;

Ozkan, Haydar ;

Feng, Steve ;

Wei, Qingshan ;

Chan, Raymond Yan-Lok ;

Burbano, Jordi ;

Farooqui, Qamar ;

Lewinski, Michael ;

Di Carlo, Dino ;

Garner, Omai B. ;

Ozcan, Aydogan .

ACS NANO, 2015, 9 (08) :7857-7866

[4] Fluorescence lateral flow immunoassay based point-of-care nanodiagnostics for orthopedic implant-associated infection [J].

Borse, Vivek ;

Srivastava, Rohit .

SENSORS AND ACTUATORS B-CHEMICAL, 2019, 280 :24-33

[5] Photoluminescence imaging of Zn2+ in living systems [J].

Chen, Yuncong ;

Bai, Yang ;

Han, Zhong ;

He, Weijiang ;

Guo, Zijian .

CHEMICAL SOCIETY REVIEWS, 2015, 44 (14) :4517-4546

[6] An integrated paper-based sample-to-answer biosensor for nucleic acid testing at the point of care [J].

Choi, Jane Ru ;

Hu, Jie ;

Tang, Ruihua ;

Gong, Yan ;

Feng, Shangsheng ;

Ren, Hui ;

Wen, Ting ;

Li, XiuJun ;

Abas, Wan Abu Bakar Wan ;

Pingguan-Murphy, Belinda ;

Xu, Feng .

LAB ON A CHIP, 2016, 16 (03) :611-621

[7] SEMIQUANTITATIVE SPECIFIC TEST PAPER FOR GLUCOSE IN URINE [J].

COMER, JP .

ANALYTICAL CHEMISTRY, 1956, 28 (11) :1748-1750

[8] The Important Role of the Apoptotic Effects of Zinc in the Development of Cancers [J].

Franklin, Renty B. ;

Costello, Leslie C. .

JOURNAL OF CELLULAR BIOCHEMISTRY, 2009, 106 (05) :750-757

[9] Prospective study of dietary pattern and risk of Parkinson disease [J].

Gao, Xiang ;

Chen, Honglei ;

Fung, Teresa T. ;

Logroscino, Giancarlo ;

Schwarzschild, Michael A. ;

Hu, Frank B. ;

Ascherio, Alberto .

AMERICAN JOURNAL OF CLINICAL NUTRITION, 2007, 86 (05) :1486-1494

[10] Three-dimensional paper-based electrochemiluminescence immunodevice for multiplexed measurement of biomarkers and point-of-care testing [J].

Ge, Lei ;

Yan, Jixian ;

Song, Xianrang ;

Yan, Mei ;

Ge, Shenguang ;

Yu, Jinghua .

BIOMATERIALS, 2012, 33 (04) :1024-1031

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