Insulin Receptor A and IGF-1R in AML - Letter

被引:6
作者
Chapuis, Nicolas [1 ,2 ,3 ]
Lacombe, Catherine [1 ,2 ,3 ]
Tamburini, Jerome [1 ,2 ]
Bouscary, Didier [1 ,2 ]
Mayeux, Patrick [1 ,2 ]
机构
[1] Univ Paris 05, CNRS, Inst Cochin, UMR8104, Paris, France
[2] INSERM, U1016, Paris, France
[3] Serv Hematol Biol, Paris, France
关键词
ACUTE MYELOID-LEUKEMIA; FACTOR-I RECEPTOR; INHIBITOR; VITRO;
D O I
10.1158/0008-5472.CAN-10-0136
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:7010 / 7010
页数:1
相关论文
共 4 条
[1]   Autocrine IGF-1/IGF-1R signaling is responsible for constitutive PI3K/Akt activation in acute myeloid leukemia: therapeutic value of neutralizing anti-IGF-1R antibody [J].
Chapuis, Nicolas ;
Tamburini, Jerome ;
Cornillet-Lefebvre, Pascale ;
Gillot, Lucile ;
Bardet, Valerie ;
Willems, Lise ;
Park, Sophie ;
Green, Alexa S. ;
Ifrah, Norbert ;
Dreyfus, Francois ;
Mayeux, Patrick ;
Lacombe, Catherine ;
Bouscary, Didier .
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2010, 95 (03) :415-423
[2]   In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417 [J].
Haluska, P ;
Carboni, JM ;
Loegering, DA ;
Lee, FY ;
Wittman, M ;
Saulnier, MG ;
Frennesson, DB ;
Kalli, KR ;
Conover, CA ;
Attar, RM ;
Kaufmann, SH ;
Gottardis, M ;
Erlichman, C .
CANCER RESEARCH, 2006, 66 (01) :362-371
[3]   Expression of Insulin Receptor Isoform A and Insulin-like Growth Factor-1 Receptor in Human Acute Myelogenous Leukemia: Effect of the Dual-Receptor Inhibitor BMS-536924 In vitro [J].
Hendrickson, Andrea E. Wahner ;
Haluska, Paul ;
Schneider, Paula A. ;
Loegering, David A. ;
Peterson, Kevin L. ;
Attar, Ricardo ;
Smith, B. Douglas ;
Erlichman, Charles ;
Gottardis, Marco ;
Karp, Judith E. ;
Carboni, Joan M. ;
Kaufmann, Scott H. .
CANCER RESEARCH, 2009, 69 (19) :7635-7643
[4]   Mammalian target of rapamycin (mTOR) inhibition activates phosphatidylinositol 3-kinase/Akt by up-regulating insulin-like growth factor-1 receptor signaling in acute myeloid leukemia: rationale for therapeutic inhibition of both pathways [J].
Tamburini, Jerome ;
Chapuis, Nicolas ;
Bardet, Valrie ;
Park, Sophie ;
Sujobert, Pierre ;
Willems, Lise ;
Ifrah, Norbert ;
Dreyfus, Francois ;
Mayeux, Patrick ;
Lacombe, Catherine ;
Bouscary, Didier .
BLOOD, 2008, 111 (01) :379-382