Bilateral somatosensory evoked potentials following intermittent theta-burst repetitive transcranial magnetic stimulation

被引：21

作者：

Premji, Azra ^{[1
]}

Ziluk, Angela ^{[1
]}

Nelson, Aimee J. ^{[1
]}

机构：

[1] Univ Waterloo, Dept Kinesiol, Waterloo, ON N2L 3G1, Canada

来源：

BMC NEUROSCIENCE | 2010年 / 11卷

基金：

加拿大自然科学与工程研究理事会;

关键词：

HUMAN MOTOR CORTEX; MEDIAN NERVE-STIMULATION; INTERHEMISPHERIC INHIBITION; CORTICAL EXCITABILITY; TACTILE PERCEPTION; SENSORIMOTOR CORTEX; HZ RTMS; IMPROVEMENT; FREQUENCY; HUMANS;

D O I：

10.1186/1471-2202-11-91

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Background: Intermittent theta-burst stimulation (iTBS) is a form of repetitive transcranial magnetic stimulation that may alter cortical excitability in the primary somatosensory cortex (SI). The present study investigated the effects of iTBS on subcortical and early cortical somatosensory evoked potentials (SEPs) recorded over left, iTBS stimulated SI and the right-hemisphere non-stimulated SI. SEPs were recorded before and at 5, 15, and 25 minutes following iTBS. Results: Compared to pre-iTBS, the amplitude of cortical potential N20/P25 was significantly increased for 5 minutes from non-stimulated SI and for 15 to 25 minutes from stimulated SI. Subcortical potentials recorded bilaterally remained unaltered following iTBS. Conclusion: We conclude that iTBS increases the cortical excitability of SI bilaterally and does not alter thalamocortical afferent input to SI. ITBS may provide one avenue to induce cortical plasticity in the somatosensory cortex.

引用

页数：7

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