Low-Cost Mini-Invasive Microwave Needle Applicator for Cancer Thermal Ablation: Feasibility Investigation

被引:8
作者
Portosi, Vincenza [1 ]
Loconsole, Antonella Maria [1 ]
Valori, Marcello [2 ]
Marrocco, Valeria [2 ]
Fassi, Irene [2 ]
Bonelli, Francesco [3 ]
Pascazio, Giuseppe [3 ]
Lampignano, Vito [4 ]
Fasano, Antonella [4 ]
Prudenzano, Francesco [1 ]
机构
[1] Politecn Bari, Dept Elect & Informat Engn, I-70126 Bari, Italy
[2] CNR, STIIMA, I-70124 Bari, Italy
[3] Politecn Bari, Dept Mech Math & Management, I-70126 Bari, Italy
[4] Neetra Srl, I-70026 Modugno, Italy
关键词
Applicators; Lesions; Dielectrics; Coaxial cables; Electromagnetic heating; Scattering parameters; Impedance matching; Cancer therapy; electromagnetic design; microwave needle; thermal ablation; FIBER LASER; ANTENNA; TISSUE; VIVO;
D O I
10.1109/JSEN.2021.3060499
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
The design and characterization of a low-cost mini-invasive needle applicator prototype for hyperthermia therapy of cancer are performed, after the investigation of different approaches, focused to increase the device feasibility and miniaturization and to improve patient wellness. The needle applicator is a coaxial antenna operating at frequency f = 2.45 GHz in the Industrial, Scientific, and Medical (ISM) frequency band. Many simulations are performed with the aim of investigating different geometries, impedance matching techniques, possible 3D-printing biocompatible materials, and radiating configurations fitting 14-gauge (14G) and 16-gauge (16G) hypodermic tube sizes. Also, a cooling circuit is investigated to maintain the patient healthy tissues at lower temperature, during the ablation session. As last step, prototypes of 14G and 16G applicators have been constructed and characterized.
引用
收藏
页码:14027 / 14034
页数:8
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