Rapid access to benzo-annelated heterocycles, naphthalenes, and polysubstituted benzenes through a novel benzannulation reaction

被引：23

作者：

Cikotiene, Inga ^{[1
]}

Buksnaitiene, Rita ^{[1
]}

Sazinas, Rokas ^{[1
]}

机构：

[1] Vilnius State Univ, Dept Organ Chem, Fac Chem, LT-03225 Vilnius, Lithuania

来源：

TETRAHEDRON | 2011年 / 67卷 / 04期

关键词：

Benzannulation; ortho-Alkynylarylaldehydes; Methyl mercaptoacetate; Microwave chemistry; RUTHENIUM-CATALYZED AROMATIZATION; HETEROAROMATIC-RING-SYSTEMS; NAPHTHYL KETONE DERIVATIVES; DOTZ BENZANNULATION; AMINOBENZANNULATION REACTION; REGIOSELECTIVE SYNTHESIS; EFFICIENT SYNTHESIS; CARBENE COMPLEXES; TERMINAL ALKYNES; CYCLIZATION;

D O I：

10.1016/j.tet.2010.11.073

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel, efficient, and powerful methyl mercaptoacetate triggered benzannulation reaction is described. The precursors are heterocyclic, aromatic or acyclic compounds bearing a carbonyl group at ortho position to an internal alkyne. The methodology does not require transition-metal catalysts and moreover it is general for the preparation of wide range of benzo-annelated heterocycles, naphthalenes and benzenes. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：706 / 717

页数：12

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