An assessment of the effects of exposure to vibration, smoking, alcohol and diabetes on the prevalence of Dupuytren's disease in 97,537 miners

被引：47

作者：

Burke, F. D. ^{[1
]}

Proud, G. ^{[1
]}

Lawson, I. J. ^{[1
]}

Mcgeoch, K. L. ^{[1
]}

Miles, J. N. V. ^{[1
]}

机构：

[1] Derbyshire Royal Infirm, Pulvertaft Hand Ctr, Derby DE1 2QY, England

来源：

JOURNAL OF HAND SURGERY-BRITISH AND EUROPEAN VOLUME | 2007年 / 32E卷 / 04期

关键词：

Dupuytren's disease : vibration; smoking; alcohol and diabetes;

D O I：

10.1016/j.jhse.2005.02.002

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

A consecutive sample of 97,537 miners seeking compensation for Hand-Arm Vibration Syndrome were examined in a medical assessment process which included documentation of age, hand dominance, Dupuytren's disease, years of vibration exposure, history of diabetes, smoking habits and units of alcohol consumption per week. The prime determinant of prevalence of Dupuytren's disease was age, and all other factors investigated were corrected for age. There was no statistically significant correlation between years of exposure to vibration and the prevalence of Dupuytren's disease. There was a statistically significant association with smoking, alcohol consumption and diabetes mellitus, with the heaviest smokers having an odds ratio (OR) of 1.31 (95% CI, 1.17, 1.47), the heaviest drinkers (in excess of 22 units a week) having an OR of 1.59 (95% CI, 1.47, 1.72) and diabetes mellitus patients having an increase in the odds of having Dupuytren's disease of 1.52 (95% CI 1.30, 1.77).

引用

页码：400 / 406

页数：7