Cell-of-Origin Assignment in Diffuse Large B-Cell Lymphoma Determined By Gene Expression in Formalin-Fixed Paraffin-Embedded Tissue Has Prognostic Significance Independent of IPI and MYC/BCL2 Immunohistochemistry

被引：2
|
作者：
Scott, David W. [1 ]
Mottok, Anja [1 ]
Ennishi, Daisuke [1 ]
Wright, George W. [2 ]
Farinha, Pedro [1 ]
Ben-Neriah, Susana [1 ]
Kridel, Robert [1 ]
Barry, Garrett S. [1 ]
Hother, Christoffer E. [1 ]
Savage, Kerry J. [1 ]
Sehn, Laurie H. [1 ]
Staudt, Louis M. [3 ]
Connors, Joseph M. [1 ]
Rimsza, Lisa M. [4 ]
Gascoyne, Randy D. [5 ]
机构：
[1] British Columbia Canc Agcy, Vancouver, BC V5Z 4E6, Canada
[2] NCI, Bethesda, MD 20892 USA
[3] NCI, Ctr Canc Res, NIH, Bethesda, MD 20892 USA
[4] Univ Arizona, Tucson, AZ USA
[5] Ctr Lymphoid Canc, Vancouver, BC, Canada
来源：
BLOOD | 2014年 / 124卷 / 21期
关键词：
D O I：
10.1182/blood.V124.21.703.703
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：3
相关论文
共 50 条
  • [41] Incidence and prognostic significance of BCL2, BCL6 and C-MYC rearrangements in diffuse large B-cell lymphoma.
    Kramer, MHH
    Hermans, J
    Philippo, K
    Geelen, E
    Wijburg, E
    vanKrieken, JHJM
    Schuuring, E
    Kluin, PM
    BLOOD, 1997, 90 (10) : 3916 - 3916
  • [42] A 220-Gene Targeted Next-Generation Sequencing Panel for the Detection of Variants in Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, and Mantle Cell Lymphoma: Application to a Cohort of 85 Formalin-Fixed Paraffin-Embedded Diffuse Large B-Cell Lymphoma Biopsies
    Friedman, Julia
    Guttapalli, Asha
    Ma, Charles
    Thodima, Venkata
    Padmanabhan, Raghavendra
    Kamalakaran, Sitharthan
    Siddiqi, Imran N.
    Houldsworth, Jane
    BLOOD, 2015, 126 (23)
  • [43] Algorithm for Assessment and Prognostic Significance of MYC and BCL2 Expression and Rearrangements in Diffuse Large B-cell Lymphoma (DLBCL) - All Wales Lymphoma Panel Study
    Pugh, M. R.
    Joshi, A.
    Attanoos, R. L.
    Dojcinov, S. D.
    JOURNAL OF PATHOLOGY, 2016, 240 : 13 - 13
  • [44] Cell-of-Origin Subtype Classification of Diffuse Large B-Cell Lymphoma Using the Lymph2Cx Assay Retains Relevance in the Context of BCL2 and MYC Expression Status
    Kendrick, Samantha L.
    Tus, Katalin
    Scott, David W.
    Wright, George
    Jaffe, Elaine S.
    Rosenwald, Andreas
    Campo, Elias
    Chan, Wing Chung
    Connors, Joseph M.
    Braziel, Rita M.
    Ott, German
    Delabie, Jan
    Cook, James R.
    Weisenburger, Dennis D.
    Greiner, Timothy C.
    Fu, Kai
    Staudt, Louis M.
    Gascoyne, Randy D.
    Rimsza, Lisa M.
    BLOOD, 2014, 124 (21)
  • [45] Concurrent Overexpression of MYC and BCL2 by Dual Immunohistochemistry Is Associated with Poor Prognosis in Diffuse Large B-cell Lymphoma
    Roh, Jin
    Yoon, Dok Hyun
    Huh, Jooryung
    Park, Chan-Sik
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2016, 146
  • [46] Clinical and pathological features of Burkitt lymphoma showing expression of BCL2-an analysis including gene expression in formalin-fixed paraffin-embedded tissue
    Masque-Soler, Neus
    Szczepanowski, Monika
    Kohler, Christian W.
    Aukema, Sietse M.
    Nagel, Inga
    Richter, Julia
    Siebert, Reiner
    Spang, Rainer
    Burkhardt, Birgit
    Klapper, Wolfram
    BRITISH JOURNAL OF HAEMATOLOGY, 2015, 171 (04) : 501 - 508
  • [47] PCR-based Clonality Analysis in Diffuse Large B-cell Lymphoma Using BIOMED-2 Primers of IgH (FR3) on Formalin-fixed Paraffin-embedded Tissue
    Kosari, Farid
    Shishehbor, Fatemeh
    Saffar, Hiva
    Sadeghipour, Alireza
    ARCHIVES OF IRANIAN MEDICINE, 2013, 16 (09) : 526 - 529
  • [48] Impact of Cell of Origin, MYC/BCL2 Dual Expression and MYC Rearrangements in Diffuse Large B-Cell Lymphoma Patients Treated with Combined Modality Therapy
    Augustyn, A.
    Gunther, J. R.
    Medeiros, L. J.
    Milgrom, S. A.
    Nastoupil, L.
    Neelapu, S. S.
    Nair, R.
    Li, S.
    Ok, C. Y.
    Steiner, R. E.
    Iyer, S. P.
    Ahmed, S.
    Westin, J.
    Rodriguez, M. A.
    Pasalic, D.
    Fayad, L.
    Samaniego, F.
    Dabaja, B.
    Pinnix, C. C.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2019, 105 (01): : S248 - S248
  • [49] Real-World Experience Using Gene Expression Profiling of Large B-Cell Lymphomas with Formalin-Fixed, Paraffin-Embedded Tissue in a Clinical Molecular Diagnostics Laboratory
    Robetorye, R.
    Ramsower, C.
    Yip, T.
    Glinsmann-Gibson, B.
    Rimsza, L.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2020, 22 (05) : S22 - S22
  • [50] Dual expression of MYC and BCL2 proteins predicts worse outcomes in diffuse large B-cell lymphoma
    Schneider, Kelli M. Clark
    Banks, Peter M.
    Collie, Angela M. B.
    Lanigan, Christopher P.
    Manilich, Elena
    Durkin, Lisa M.
    Hill, Brian T.
    Hsi, Eric D.
    LEUKEMIA & LYMPHOMA, 2016, 57 (07) : 1640 - 1648
12345