Reactivation and centripetal spread of herpes simplex virus complicating acoustic neuroma resection

被引:17
作者
Jalloh, Ibrahim [1 ]
Guilfoyle, Mathew R. [1 ]
Lloyd, Simon K. W. [2 ]
Macfarlane, Robert [1 ]
Smith, Chris [3 ]
机构
[1] Cambridge Univ Hosp NHS Fdn Trust, Addenbrookes Hosp, Dept Neurosurg, Cambridge CB2 2QQ, England
[2] Cambridge Univ Hosp NHS Fdn Trust, Addenbrookes Hosp, Dept Otorhinolaryngol, Cambridge CB2 2QQ, England
[3] Cambridge Univ Hosp NHS Fdn Trust, Addenbrookes Hosp, Dept Virol, Cambridge CB2 2QQ, England
来源
SURGICAL NEUROLOGY | 2009年 / 72卷 / 05期
关键词
Acoustic neuroma; Herpes simplex; Reactivation; DELAYED FACIAL PALSY; ENCEPHALITIS; NEUROSURGERY; PREVALENCE;
D O I
10.1016/j.surneu.2008.11.002
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background: Herpes simplex is a common human pathogen that has rare but severe manifestations including encephalitis. Case Description: A 44-year-old man underwent uneventful resection of an acoustic neuroma. Postoperatively, he developed swinging pyrexia, vomiting, and episodic confusion. Analysis of cerebrospinal fluid showed a lymphocytosis, and polymerase chain reaction revealed herpes simplex DNA. After treatment of herpes encephalitis with acyclovir, the patient made a good recovery. Conclusion: Herpes encephalitis is a rare complication of neurosurgical procedures, and the most likely etiology is reactivation of latent infection from manipulation of cranial nerves. (C) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码:502 / 504
页数:3
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