Synthesis of some biologically active pyrimidine and isoxazole derivatives

被引：0

作者：

Mistry, B. D. ^{[1
]}

Desai, K. R. ^{[1
]}

Intwala, S. M. ^{[1
]}

机构：

[1] BKM Sci Coll, Dept Chem, Valsad 396001, Gujarat, India

来源：

JOURNAL OF THE INDIAN CHEMICAL SOCIETY | 2014年 / 91卷 / 12期

关键词：

Thienyl; pyrimidine; isoxazole; antibacterial; antifungal; MICROWAVE;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

4-(2,5-Dichloro-3-thienyl)-6-substitutedphenylpyrimidine-2(1H)-thione (2a-j), 3-(2,5-dichloro-3-thieny1)-5-substitutedpheny1-4,5-dihydroisoxazole (3a-j) have been synthesized by the reaction of (2E)-1-(2,5-dichloro-3-thienyl)-3-substitutedphenylprop-2-en-1-one (1) with thiourea and hydoxylamine hydrochloride respectively. These compounds have been screened for their antibacterial and antifungal activities against different microorganisms. The structures of novel synthesized compounds have been established on the basis of elemental analysis, IR, H-1 NMR, C-13 NMR and mass spectral data.

引用

页码：2263 / 2269

页数：7

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