Two new triterpenoid glycosides from the stems of Camellia oleifera Abel

被引：14

作者：

Yan, Qing-Wei ^{[1
,2
]}

Fu, Hui-Zheng ^{[1
]}

Luo, Yue-Hua ^{[1
]}

Zhou, Guo-Ping ^{[1
]}

Wan, Kai-Hua ^{[3
]}

Zhong, Rui-Jian ^{[1
]}

机构：

[1] Jiangxi Prov Engn Res Ctr Drug & Med Device Qual, Jiangxi Prov Inst Drug Control, Nanchang, Peoples R China

[2] Nanchang Univ, Pharmaceut Dept, Nanchang, Peoples R China

[3] Drug Adverse React Monitoring Ctr Jiangxi, Nanchang, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2016年 / 30卷 / 13期

关键词：

Camellia oleifera Abel; Theaceae; triterpenoid glycosides; SAPONINS;

D O I：

10.1080/14786419.2015.1113529

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two new oleanane-type triterpenoid glycosides, 3-O--D-xylopyranosyl-(12)--L-arabinopyranosyl-(13)-[-D-glucuronopyranosyl-(12)]--D-glucuronopyranosyl-22-angeloyloxyolean-12-ene-15,16,28-triol(1) and 3-O--D-xylopyranosyl-(12)--L-arabinopyranosyl-(13)-[-D-glucuronopyranosyl-(12)]--D-glucuronopyranosyl-21-acetyl-22-angeloyloxyolean-12-ene-16,28-diol (2) were isolated from the stems of Camellia oleifera Abel. Their structures were elucidated by means of spectroscopic methods and chemical evidence. The cytotoxic activities of compounds 1-2 were evaluated against five human tumour cell lines (HCT-8, BGC-823, A5049, and A2780). Compounds 1-2 showed cytotoxic activity against five human cancer cell lines, with IC50 values ranging from 3.15 to 7.32 mu M. [GRAPHICS] .

引用

页码：1484 / 1492

页数：9

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