Management of metastatic colorectal cancer patients: guidelines of the Italian Medical Oncology Association (AIOM)

被引：37

作者：

Salvatore, Lisa ^{[1
]}

Aprile, Giuseppe ^{[2
]}

Arnoldi, Ermenegildo ^{[3
]}

Aschele, Carlo ^{[4
]}

Carnaghi, Carlo ^{[5
]}

Cosimelli, Maurizio ^{[6
]}

Maiello, Evaristo ^{[7
]}

Normanno, Nicola ^{[8
]}

Sciallero, Stefania ^{[9
]}

Valvo, Francesca ^{[10
]}

Beretta, Giordano D. ^{[11
]}

机构：

[1] Azienda Ospedaliero Univ Integrata Verona, Dept Oncol, Verona, Italy

[2] Osped San Bortolo, Dept Oncol, Vicenza, Italy

[3] Azienda Ospedaliera Papa Giovanni XXIII, Dept Oncol, Bergamo, Italy

[4] ASL5 Liguria, Dept Oncol, La Spezia, Italy

[5] Humanitas Canc Ctr, Dept Oncol, Rozzano, MI, Italy

[6] Ist Nazl Tumori Regina Elena, Dept Oncol Surg, Rome, Italy

[7] Osped Casa Sollievo Sofferenza, Dept Oncol, San Giovanni Rotondo, Puglia, Italy

[8] Ist Nazl Tumori Fondazione G Pascale IRCCS, Dept Cell Biol & Biotherapies, Naples, Italy

[9] Azienda Ospedaliera S Martino IRCCS, Dept Oncol, IST, Genoa, Italy

[10] Ctr Nazl Adroterapia, Dept Radiotherapy, Pavia, Italy

[11] Humanitas Gavazzeni, Dept Oncol, Bergamo, Italy

来源：

ESMO OPEN | 2017年 / 2卷 / 01期

关键词：

PHASE-III TRIAL; CAPECITABINE PLUS OXALIPLATIN; RESECTABLE LIVER METASTASES; 1ST-LINE TREATMENT; COMBINATION CHEMOTHERAPY; RANDOMIZED-TRIAL; OPEN-LABEL; ORAL FLUOROPYRIMIDINES; IMPROVES SURVIVAL; PANITUMUMAB PLUS;

D O I：

10.1136/esmoopen-2016-000147

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In the past 15 years, the outcome for patients with metastatic colorectal cancer has substantially improved owing to the availability of new cytotoxic and biological agents along with many significant advances in molecular selection, the use of personalised therapy and locoregional treatment, a more widespread sharing of specific professional experiences (multidisciplinary teams with oncologists, surgeons, radiotherapists, radiologists, biologists and pathologists), and the adoption of patientcentred healthcare strategies. The Italian Medical Oncology Association (AIOM) has developed evidence-based recommendations to help oncologists and all professionals involved in the management of patients with metastatic colorectal cancer in their daily clinical practice.

引用

页数：11

共 70 条

[61] OPTIMOX1:: A randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-go fashion in advanced colorectal cancer -: A GERCOR study [J].

Tournigand, C ;

Cervantes, A ;

Figer, A ;

Lledo, G ;

Flesch, M ;

Buyse, M ;

Mineur, L ;

Carola, E ;

Etienne, PL ;

Rivera, F ;

Chirivella, I ;

Perez-Staub, N ;

Louvet, C ;

André, T ;

Tabah-Fisch, I ;

de Gramont, A .

JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (03) :394-400

[62] FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer:: A randomized GERCOR study [J].

Tournigand, C ;

André, T ;

Achille, E ;

Lledo, G ;

Flesh, M ;

Mery-Mignard, D ;

Quinaux, E ;

Couteau, C ;

Buyse, M ;

Ganem, G ;

Landi, B ;

Colin, P ;

Louvet, C ;

de Gramont, A .

JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (02) :229-237

[63] Phase III Trial of Cetuximab With Continuous or Intermittent Fluorouracil, Leucovorin, and Oxaliplatin (Nordic FLOX) Versus FLOX Alone in First-Line Treatment of Metastatic Colorectal Cancer: The NORDIC-VII Study [J].

Tveit, Kjell Magne ;

Guren, Tormod ;

Glimelius, Bengt ;

Pfeiffer, Per ;

Sorbye, Halfdan ;

Pyrhonen, Seppo ;

Sigurdsson, Fridbjorn ;

Kure, Elin ;

Ikdahl, Tone ;

Skovlund, Eva ;

Fokstuen, Tone ;

Hansen, Flemming ;

Hofsli, Eva ;

Birkemeyer, Elke ;

Johnsson, Anders ;

Starkhammar, Hans ;

Yilmaz, Mette Karen ;

Keldsen, Nina ;

Erdal, Anne Berit ;

Dajani, Olav ;

Dahl, Olav ;

Christoffersen, Thoralf .

JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15) :1755-1762

[64] Safety and efficacy of first-line bevacizumab with FOLFOX, XELOX, FOLFIRI and fluoropyrimidines in metastatic colorectal cancer: the BEAT study [J].

Van Cutsem, E. ;

Rivera, F. ;

Berry, S. ;

Kretzschmar, A. ;

Michael, M. ;

DiBartolomeo, M. ;

Mazier, M. -A. ;

Canon, J. -L. ;

Georgoulias, V. ;

Peeters, M. ;

Bridgewater, J. ;

Cunningham, D. .

ANNALS OF ONCOLOGY, 2009, 20 (11) :1842-1847

[65] Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer [J].

Van Cutsem, Eric ;

Peeters, Marc ;

Siena, Salvatore ;

Humblet, Yves ;

Hendlisz, Alain ;

Neyns, Bart ;

Canon, Jean-Luc ;

Van Laethem, Jean-Luc ;

Maurel, Joan ;

Richardson, Gary ;

Wolf, Michael ;

Amado, Rafael G. .

JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (13) :1658-1664

[66] Addition of Aflibercept to Fluorouracil, Leucovorin, and Irinotecan Improves Survival in a Phase III Randomized Trial in Patients With Metastatic Colorectal Cancer Previously Treated With an Oxaliplatin-Based Regimen [J].

Van Cutsem, Eric ;

Tabernero, Josep ;

Lakomy, Radek ;

Prenen, Hans ;

Prausova, Jana ;

Macarulla, Teresa ;

Ruff, Paul ;

van Hazel, Guy A. ;

Moiseyenko, Vladimir ;

Ferry, David ;

McKendrick, Joe ;

Polikoff, Jonathan ;

Tellier, Alexia ;

Castan, Remi ;

Allegra, Carmen .

JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (28) :3499-3506

[67] Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer [J].

Van Cutsem, Eric ;

Koehne, Claus-Henning ;

Hitre, Erika ;

Zaluski, Jerzy ;

Chien, Chung-Rong Chang ;

Makhson, Anatoly ;

D'Haens, Geert ;

Pinter, Tamas ;

Lim, Robert ;

Bodoky, Gyoergy ;

Roh, Jae Kyung ;

Folprecht, Gunnar ;

Ruff, Paul ;

Stroh, Christopher ;

Tejpar, Sabine ;

Schlichting, Michael ;

Nippgen, Johannes ;

Rougier, Philippe .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (14) :1408-1417

[68] SIRFLOX: Randomized Phase III Trial Comparing First-Line mFOLFOX6 (Plus or Minus Bevacizumab) Versus mFOLFOX6 (Plus or Minus Bevacizumab) Plus Selective Internal Radiation Therapy in Patients With Metastatic Colorectal Cancer [J].

van Hazel, Guy A. ;

Heinemann, Volker ;

Sharma, Navesh K. ;

Findlay, Michael P. N. ;

Ricke, Jens ;

Peeters, Marc ;

Perez, David ;

Robinson, Bridget A. ;

Strickland, Andrew H. ;

Ferguson, Tom ;

Rodriguez, Javier ;

Kroening, Hendrik ;

Wolf, Ido ;

Ganju, Vinod ;

Walpole, Euan ;

Boucher, Eveline ;

Tichler, Thomas ;

Shacham-Shmueli, Einat ;

Powell, Alex ;

Eliadis, Paul ;

Isaacs, Richard ;

Price, David ;

Moeslein, Fred ;

Taieb, Julien ;

Bower, Geoff ;

Gebski, Val ;

Van Buskirk, Mark ;

Cade, David N. ;

Thurston, Kenneth ;

Gibbs, Peter .

JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15) :1723-+

[69]

Venook AP, 2014, J CLIN ONCOL, V32, P3

[70] Randomized trial of cytoreduction and hyperthermic intraperitoneal chemotherapy versus systemic chemotherapy and palliative surgery in patients with peritoneal carcinomatosis of colorectal cancer [J].

Verwaal, VJ ;

van Ruth, S ;

de Bree, E ;

van Slooten, GW ;

van Tinteren, H ;

Boot, H ;

Zoetmulder, FAN .

JOURNAL OF CLINICAL ONCOLOGY, 2003, 21 (20) :3737-3743

← 1 2 3 4 5 6 7 →