Impact analysis of expanding narrow-spectrum antibiotic use for children with ear, sinus and throat infections

被引：2

作者：

Barbosa, Carolina ^{[1
]}

Breck, Andrew ^{[2
]}

King, Grant ^{[1
]}

Bass, Sarah ^{[1
]}

Kook, Yoojin ^{[2
]}

Honeycutt, Amanda ^{[1
]}

Esposito, Dominick ^{[2
]}

机构：

[1] RTI Int, Hlth Econ Program, Durham, NC 27709 USA

[2] Insight Policy Res, Arlington, VA 22209 USA

来源：

JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH | 2021年 / 11卷 / 02期

关键词：

acute respiratory tract infections; acute sinusitis; antibiotic use; decision tree model; group A strep; healthcare expenditures; otitis media; ACUTE OTITIS-MEDIA; PENICILLIN ALLERGY; PHARYNGITIS; MANAGEMENT; EVENTS; UPDATE; COSTS;

D O I：

10.2217/cer-2021-0064

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Aim: Estimate the impacts treating acute respiratory tract infections (ARTIs) in children aged 6 months through 12 years with narrow-spectrum antibiotics. Materials & methods: Decision-tree model to estimate children's health, healthcare utilization and costs, and caregiver's time and costs for using narrow-spectrum antibiotics in eligible children with an ARTI, compared with current use of narrow- and broad-spectrum antibiotics. Results: Reduced adverse drug reactions by 35,750 (14%) cases) and 4750 (12%) fewer emergency department visits, 300 (12%) fewer hospitalizations, and 50,500 (10%) avoided outpatient visits. Annual healthcare costs fell by US$120 million (22%). Total societal costs declined by US$131 million (20%). Conclusion: National implementation of narrow-spectrum antibiotics to treat ARTIs in children improves patient outcomes and reduces caregiver burden and annual healthcare costs.

引用

页码：89 / 98

页数：10

共 38 条

[1]

AHRQ (Agency for Healthcare Hesearch and Quality), 2019, MEPS MED EXP PAN SUR

[2] A systematic review and meta-analysis of the effects of antibiotic consumption on antibiotic resistance [J].