A pilot study on the off-label use of valproic acid to treat adenomyosis

被引:68
作者
Liu, Xishi [2 ,3 ]
Guo, Sun-Wei [1 ]
机构
[1] Med Coll Wisconsin, Dept Pediat, Milwaukee, WI 53226 USA
[2] Shanghai Obstet & Gynecol Hosp, Dept Gynecol, Shanghai 200011, Peoples R China
[3] Fudan Univ, Shanghai Med Sch, Dept Gynecol & Obstet, Shanghai 200433, Peoples R China
关键词
D O I
10.1016/j.fertnstert.2006.11.009
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Following on the heels of the discovery that endometriosis is an epigenetic disease, we conducted a pilot study on the off-label use of valproic acid to treat adenomyosis. We found that by the end of the 3-month treatment, all three recruited patients reported complete disappearance of dysmenorrhea, with an average of one-third reduction in uterus size.
引用
收藏
页码:246 / 250
页数:5
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